Abstract:
In this paper the authors present a method for analytically calculating the distribution of photons detected in single photon emission computed tomography (SPECT) project...Show MoreMetadata
Abstract:
In this paper the authors present a method for analytically calculating the distribution of photons detected in single photon emission computed tomography (SPECT) projections. The technique is applicable to sources in homogeneous and nonhomogeneous media. The photon distribution (primary, first-, and second-order Compton scatter) is computed using a precalculated camera-dependent look-up table in conjunction with an attenuation map of the scattering object and a map of the activity distribution. The speed and accuracy of this technique is compared to that of Monte Carlo simulations. The cases considered are a point source in a homogeneous and also in a nonhomogeneous scattering medium, an extended source in a nonhomogeneous medium, and a homogeneous cylinder filled uniformly with activity. The method is quantitatively accurate and faithfully reproduces the spatial distribution of the unscattered and scattered photons. For comparable statistical precision in the peak of the calculated distribution, their approach can result in a gain in calculation time over Monte Carlo simulators. For point sources, the computation times are improved by a factor of 20-150. However, this gain depends on the source configuration, and calculation times become comparable for an 800 voxel source and are five times slower for a 55000 voxel source. The method also offers an increase in the speed of computation of higher order Compton scatter events over a similar analytical technique.
Published in: IEEE Transactions on Nuclear Science ( Volume: 45, Issue: 6, December 1998)
DOI: 10.1109/23.736199
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Cites in Papers - IEEE (26)
Select All
1.
Thomas Humphries, Anna Celler, Manfred Trummer, "Effects of attenuation in single slow rotation dynamic SPECT", 2011 IEEE Nuclear Science Symposium Conference Record, pp.3725-3731, 2011.
2.
S. Shcherbinin, J. Grimes, A. Celler, "An adaptive generation of a digital mask to improve activity distribution in SPECT images", 2011 IEEE Nuclear Science Symposium Conference Record, pp.3752-3759, 2011.
3.
S. Shcherbinin, A. Celler, "Do template-based partial volume effect corrections inherently presume homogeneous uptakes?", 2011 IEEE Nuclear Science Symposium Conference Record, pp.3764-3771, 2011.
4.
S. Shcherbinin, A. Celler, "Simultaneous crosstalk compensation for a ROI activity estimation in dual-isotope SPECT imaging", 2009 IEEE Nuclear Science Symposium Conference Record (NSS/MIC), pp.3256-3261, 2009.
5.
S. Shcherbinin, A. Celler, "A physical phantom evaluation of absolute quantitation of simultaneous Tc-99m/In-111 SPECT", 2009 IEEE Nuclear Science Symposium Conference Record (NSS/MIC), pp.3736-3740, 2009.
6.
Tyler Hughes, Sergey Shcherbinin, Anna Celler, "A new approach in patient motion correction for cardiac SPECT: A simulation study", 2009 IEEE Nuclear Science Symposium Conference Record (NSS/MIC), pp.3203-3206, 2009.
7.
S. Shcherbinin, A. Celler, "Quantitative accuracy of SPECT reconstructions with a voxelized CT-based partial volume effect correction", 2008 IEEE Nuclear Science Symposium Conference Record, pp.4311-4318, 2008.
8.
Eric Vandervoort, Vesna Sossi, "An Analytical Scatter Correction for Singles-Mode Transmission Data in PET", IEEE Transactions on Medical Imaging, vol.27, no.3, pp.402-412, 2008.
9.
T. Humphries, A. Celler, M.R. Trummer, "Improved numerical integration for analytical photon distribution calculation in SPECT", 2007 IEEE Nuclear Science Symposium Conference Record, vol.5, pp.3548-3554, 2007.
10.
Arkadiusz Sitek, Georges El Fakhri, Jinsong Ouyang, Jonathan S. Maltz, "Fast analytical modeling of Compton scatter using point clouds and graphics processing unit (GPU)", 2007 IEEE Nuclear Science Symposium Conference Record, vol.6, pp.4546-4548, 2007.
11.
Yan Yan, Gengsheng L. Zeng, "A Post-Processing Method of Scatter Modeling in SPECT", 2006 IEEE Nuclear Science Symposium Conference Record, vol.5, pp.2649-2652, 2006.
12.
Ivan G. Kazantsev, Samuel Matej, Robert M. Lewitt, "Geometric model of single scatter in PET", 2006 IEEE Nuclear Science Symposium Conference Record, vol.5, pp.2740-2743, 2006.
13.
S. Shcherbinin, A. Celler, M. Trummer, T. Humphries, "An APD-based Iterative Reconstruction Method for Simultaneous Technetium-99m/lodine-123 SPECT Imaging", 2006 IEEE Nuclear Science Symposium Conference Record, vol.4, pp.2058-2062, 2006.
14.
Eric Vandervoort, Vesna Sossi, "An analytical scatter correction for singles-mode transmission data in PET", 2006 IEEE Nuclear Science Symposium Conference Record, vol.6, pp.3310-3314, 2006.
15.
S. Bergner, E. Dagenais, A. Celler, T. Moller, "Using the physics-based rendering toolkit for medical reconstruction", IEEE Nuclear Science Symposium Conference Record, 2005, vol.5, pp.3022-3026, 2005.
16.
E. Vandervoort, A. Celler, G. Wells, S. Blinder, K. Dixon, Yanxin Pang, "Implementation of an analytically based scatter correction in SPECT reconstructions", IEEE Transactions on Nuclear Science, vol.52, no.3, pp.645-653, 2005.
17.
E. Vandervoort, A. Celler, G. Wells, S. Blinder, K. Dixon, Yanxin Pang, "The influence of attenuation-map quality on the absolute quantitative accuracy of SPECT images", IEEE Symposium Conference Record Nuclear Science 2004., vol.5, pp.2700-2704, 2004.
18.
E. Vandervoort, A. Celler, G. Wells, S. Blinder, K. Dixon, Y. Pang, "Implementation of an analytically based scatter correction in SPECT reconstructions", 2003 IEEE Nuclear Science Symposium. Conference Record (IEEE Cat. No.03CH37515), vol.4, pp.2647-2651 Vol.4, 2003.
19.
Tianyu Ma, Yongjie Jin, "Efficient analytical scatter modeling in fully 3-D iterative single photon emission computed tomography reconstruction", 2003 IEEE Nuclear Science Symposium. Conference Record (IEEE Cat. No.03CH37515), vol.5, pp.3137-3141 Vol.5, 2003.
20.
F.J. Beekman, H.W.A.M. de Jong, S. van Geloven, "Efficient fully 3-D iterative SPECT reconstruction with Monte Carlo-based scatter compensation", IEEE Transactions on Medical Imaging, vol.21, no.8, pp.867-877, 2002.
21.
F.J. Beekman, H.W.A.M. de Jong, S. van Geloven, "Efficient Monte Carlo based reconstruction for general quantitative SPECT", 2001 IEEE Nuclear Science Symposium Conference Record (Cat. No.01CH37310), vol.4, pp.1864-1868 vol.4, 2001.
22.
C. Bai, G.L. Zeng, G.T. Gullberg, "The modeling of multiple order Compton scatter in SPECT", IEEE Transactions on Nuclear Science, vol.48, no.1, pp.38-42, 2001.
23.
R.G. Wells, A. Celler, R. Harrop, "Analytical calculations of cross-talk for dual-isotope SPECT projections", IEEE Transactions on Nuclear Science, vol.47, no.3, pp.1202-1209, 2000.
24.
A. Celler, D. Axen, D. Togane, J. El-Khatib, "Investigation of scatter in SPECT transmission studies", IEEE Transactions on Nuclear Science, vol.47, no.3, pp.1251-1257, 2000.
25.
Chuanyong Bai, G.L. Zeng, G.T. Gullberg, "The modeling of multiple order Compton scatter in SPECT", 1999 IEEE Nuclear Science Symposium. Conference Record. 1999 Nuclear Science Symposium and Medical Imaging Conference (Cat. No.99CH37019), vol.3, pp.1490-1494 vol.3, 1999.
26.
R.G. Wells, A. Celler, R. Harrop, "Analytical calculations of cross-talk for dual-isotope SPECT projections", 1997 IEEE Nuclear Science Symposium Conference Record, vol.2, pp.1513-1517 vol.2, 1997.
Cites in Papers - Other Publishers (49)
1.
Johan Gustafsson, Jan Taprogge, "Future trends for patient-specific dosimetry methodology in molecular radiotherapy", Physica Medica, pp.103165, 2023.
2.
S. A. Tereshchenko, A. Yu. Lysenko, "Single-photon emission computed tomography in the scattering medium with the property of ?scattering straight back?", Journal of Applied Physics, vol.129, no.3, pp.035101, 2021.
3.
Johan Gustafsson, Gustav Brolin, Michael Ljungberg, "Monte Carlo-based SPECT reconstruction within the SIMIND framework", Physics in Medicine & Biology, vol.63, no.24, pp.245012, 2018.
4.
Philipp Ritt, Harald H. Quick, Medizinische Physik, pp.365, 2018.
5.
Pedro L Esquinas, Carlos F Uribe, M Gonzalez, Cristina Rodriguez-Rodriguez, Urs O Hafeli, Anna Celler, "Accuracy of Rhenium-188 SPECT/CT activity quantification for applications in radionuclide therapy using clinical reconstruction methods", Physics in Medicine & Biology, vol.62, no.16, pp.6379, 2017.
6.
Carlos F. Uribe, Pedro L. Esquinas, Jesse Tanguay, Marjorie Gonzalez, Emilie Gaudin, Jean-Mathieu Beauregard, Anna Celler, "Accuracy of 177Lu activity quantification in SPECT imaging: a phantom study", EJNMMI Physics, vol.4, no.1, 2017.
7.
Amir Pourmoghaddas, R. Glenn Wells, "Analytically based photon scatter modeling for a multipinhole cardiac SPECT camera", Medical Physics, vol.43, no.11, pp.6098, 2016.
8.
Benjamin Auer, Clement Rey, Virgile Bekaert, Jean-Michel Gallone, Ziad El Bitar, "Implementation of a pre-calculated database approach for scatter correction in SPECT", Biomedical Physics & Engineering Express, vol.2, no.5, pp.055014, 2016.
9.
M.A. King, P.H. Pretorius, Comprehensive Biomedical Physics, pp.93, 2014.
10.
S Shcherbinin, J Grimes, A Bator, J B Cwikla, A Celler, "Three-dimensional personalized dosimetry for188Re liver selective internal radiation therapy based on quantitative post-treatment SPECT studies", Physics in Medicine and Biology, vol.59, no.1, pp.119, 2014.
11.
Philipp Ritt, Torsten Kuwert, Molecular Imaging in Oncology, vol.187, pp.313, 2013.
12.
S Shcherbinin, S Chamoiseau, A Celler, "Simulation-based reconstruction of absolute activities from the99mTc/111In dual-isotope SPECT/CT: phantom experiments and imaging of neuroendocrine tumors", Physics in Medicine and Biology, vol.58, no.10, pp.3339, 2013.
13.
S Shcherbinin, J Grimes, A Celler, "Two methods to generate templates for template-based partial volume effect correction: SPECT phantom experiments", Physics in Medicine and Biology, vol.58, no.4, pp.1103, 2013.
14.
Kenneth Koral, Yuni Dewaraja, "Monte Carlo in SPECT Scatter Correction", Monte Carlo Calculations in Nuclear Medicine, Second Edition, vol.20126027, pp.221, 2012.
15.
S Shcherbinin, H Piwowarska-Bilska, A Celler, B Birkenfeld, "Quantitative SPECT/CT reconstruction for177Lu and177Lu/90Y targeted radionuclide therapies", Physics in Medicine and Biology, vol.57, no.18, pp.5733, 2012.
16.
Abhinav K. Jha, Matthew A. Kupinski, Harrison H. Barrett, Eric Clarkson, John H. Hartman, "Three-dimensional Neumann-series approach to model light transport in nonuniform media", Journal of the Optical Society of America A, vol.29, no.9, pp.1885, 2012.
17.
Abhinav K. Jha, Matthew A. Kupinski, Takahiro Masumura, Eric Clarkson, Alexey V. Maslov, Harrison H. Barrett, "Simulating photon-transport in uniform media using the radiative transport equation: a study using the Neumann-series approach", Journal of the Optical Society of America A, vol.29, no.8, pp.1741, 2012.
18.
Joshua Grimes, Anna Celler, Sergey Shcherbinin, Hanna Piwowarska-Bilska, Bozena Birkenfeld, "The accuracy and reproducibility of SPECT target volumes and activities estimated using an iterative adaptive thresholding technique", Nuclear Medicine Communications, vol.33, no.12, pp.1254, 2012.
19.
Eric C. Frey, John L. Humm, Michael Ljungberg, "Accuracy and Precision of Radioactivity Quantification in Nuclear Medicine Images", Seminars in Nuclear Medicine, vol.42, no.3, pp.208, 2012.
20.
S Shcherbinin, S Chamoiseau, A Celler, "Quantitative image reconstruction for dual-isotope parathyroid SPECT/CT: phantom experiments and sample patient studies", Physics in Medicine and Biology, vol.57, no.15, pp.4755, 2012.
21.
Joshua Grimes, Anna Celler, Bozena Birkenfeld, Sergey Shcherbinin, Maria H. Listewnik, Hanna Piwowarska-Bilska, Renata Mikołajczak, Piotr Zorga, "Patient-Specific Radiation Dosimetry of 99mTc-HYNIC-Tyr3-Octreotide in Neuroendocrine Tumors", Journal of Nuclear Medicine, vol.52, no.9, pp.1474, 2011.
22.
S Shcherbinin, A Celler, "Assessment of the severity of partial volume effects and the performance of two template-based correction methods in a SPECT/CT phantom experiment", Physics in Medicine and Biology, vol.56, no.16, pp.5355, 2011.
23.
Brian F Hutton, Irene Buvat, Freek J Beekman, "Review and current status of SPECT scatter correction", Physics in Medicine and Biology, vol.56, no.14, pp.R85, 2011.
24.
Philipp Ritt, Hans Vija, Joachim Hornegger, Torsten Kuwert, "Absolute quantification in SPECT", European Journal of Nuclear Medicine and Molecular Imaging, vol.38, no.S1, pp.69, 2011.
25.
E Rault, S Staelens, R Van Holen, J De Beenhouwer, S Vandenberghe, "Accurate Monte Carlo modelling of the back compartments of SPECT cameras", Physics in Medicine and Biology, vol.56, no.1, pp.87, 2011.
26.
Lingshu Yin, Sergey Shcherbinin, Anna Celler, Anna Thompson, Tsien-Fei Fua, Mitchell Liu, Cheryl Duzenli, Brad Gill, Finbar Sheehan, John Powe, Daniel Worsley, Lawrence Marks, Vitali Moiseenko, "Incorporating Quantitative Single Photon Emission Computed Tomography into Radiation Therapy Treatment Planning for Lung Cancer: Impact of Attenuation and Scatter Correction on the Single Photon Emission Computed Tomography–Weighted Mean Dose and Functional Lung Segmentation", International Journal of Radiation Oncology*Biology*Physics, vol.78, no.2, pp.587, 2010.
27.
S Shcherbinin, A Celler, "Quantitative accuracy of the closed-form least-squares solution for targeted SPECT", Physics in Medicine and Biology, vol.55, no.19, pp.5667, 2010.
28.
S. Shcherbinin, A. Celler, "An enhancement of quantitative accuracy of the SPECT/CT activity distribution reconstructions: Physical phantom experiments", Computerized Medical Imaging and Graphics, vol.34, no.5, pp.346, 2010.
29.
Anna Celler, Sergey Shcherbinin, Tyler Hughes, "An investigation of potential sources of artifacts in SPECT-CT myocardial perfusion studies", Journal of Nuclear Cardiology, vol.17, no.2, pp.232, 2010.
30.
Bai Chuanyong, Hetal Babla, Richard Conwell, "Emission-based scatter correction in SPECT imaging", Tsinghua Science and Technology, vol.15, no.1, pp.1-10, 2010.
