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Sik-Ho Tsang - IEEE Xplore Author Profile

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Objective: We propose a procedure for calibrating 4 parameters governing the mechanical boundary conditions (BCs) of a thoracic aorta (TA) model derived from one patient with ascending aortic aneurysm. The BCs reproduce the visco-elastic structural support provided by the soft tissue and the spine and allow for the inclusion of the heart motion effect. Methods: We first segment the TA from magneti...Show More
Cardiac left ventricular (LV) segmentation is a paramount essential step for both diagnosis and treatment of cardiac pathologies such as ischemia, myocardial infarction, arrhythmia and myocarditis. However, this segmentation is challenging due to high variability across patients and the potential lack of contrast between structures. In this work, we propose and evaluate a (2.5D) SegU-Net model bas...Show More
Deep learning has successfully been leveraged for medical image segmentation. It employs convolutional neural networks (CNN) to learn distinctive image features from a defined pixel-wise objective function. However, this approach can lead to less output pixel interdependence producing incomplete and unrealistic segmentation results. In this paper, we present a fully automatic deep learning method ...Show More
Accurate three-dimensional (3D) cardiac segmentation from late gadolinium enhancement (LGE)-MRI plays a critical role in designing a structure of reference for diagnosing many cardiac pathologies such as ischemia, myocarditis and myocardial infarction. This segmentation is however still a non-trivial task, due to the motion artifacts during acquisition, and heterogeneous intensity distributions. I...Show More
In this paper, we propose an automatic myocardial infarction segmentation framework from Delayed Enhancement cardiac MRI (DE-MRI) using a convolutional neural network (CNN) and prior information-based post-treatments. The work was conducted on our DE-MRI dataset, which is collected from daily clinical practice. 195 cases of DE-MRI examinations constitute this dataset, including on average 7 images...Show More
Convolutional neural networks (CNN) have had unprecedented success in medical imaging and, in particular, in medical image segmentation. However, despite the fact that segmentation results are closer than ever to the inter-expert variability, CNNs are not immune to producing anatomically inaccurate segmentations, even when built upon a shape prior. In this paper, we present a framework for produci...Show More
Cranial base procedures involve manipulation of small, delicate and complex structures in the fields of otology, rhinology, neurosurgery and maxillofacial surgery. Critical nerves and blood vessels are in close proximity of these structures. Augmented reality is an emerging technology that can revolutionize the cranial base procedures by providing supplementary anatomical and navigational informat...Show More
Skin lesion segmentation in dermoscopic images is still a challenge due to the low contrast and fuzzy boundaries of lesions. Moreover, lesions have high similarity with the healthy regions in terms of appearance. In this paper, we propose an accurate skin lesion segmentation model based on a modified conditional generative adversarial network (cGAN). We introduce a new block in the encoder of cGAN...Show More
In this paper, we present a novel convolutional neural network architecture to segment images from a series of short-axis cardiac magnetic resonance slices (CMRI). The proposed model is an extension of the U-net that embeds a cardiac shape prior and involves a loss function tailored to the cardiac anatomy. Since the shape prior is computed offline only once, the execution of our model is not limit...Show More
Delineation of the left ventricular cavity, myocardium, and right ventricle from cardiac magnetic resonance images (multi-slice 2-D cine MRI) is a common clinical task to establish diagnosis. The automation of the corresponding tasks has thus been the subject of intense research over the past decades. In this paper, we introduce the “Automatic Cardiac Diagnosis Challenge” dataset (ACDC), the large...Show More
This paper presents a new methodology providing the first step towards generating attenuation maps for PET/MR systems based solely on MR information. The new method segments and classifies the attenuation-differing regions of the patient's pelvis based on acquired T1- and T2-weighted MR data sets and anatomical-based knowledge by computing the tissue specific T1 and T2 relaxation times, using a ro...Show More
Single-photon emission computed tomography (SPECT) imaging of the heart is helpful to quantify the left-ventricular ejection fraction and study myocardial perfusion scans. However, these evaluations require a 3-D segmentation of the left-ventricular wall on each phase of the cardiac cycle. This paper presents a fast and interactive graph cut method for 3-D segmentation of the left ventricle (LV) o...Show More
In this paper, we consider the estimation of a reference shape from a set of different segmentation results using both active contours and information theory. The reference shape is defined as the minimum of a criterion that benefits from both the mutual information and the joint entropy of the input segmentations and is then called a mutual shape. This energy criterion is here justified using sim...Show More
This paper presents a method for local myocardial motion estimation from a conventional steady-state free precession cine-MRI sequence using a modified phase-based optical flow (OF) technique. Initially, the technique was tested on synthetic images to evaluate its robustness with regards to Rician noise and to brightness variations. The method was then applied to cardiac images acquired on 11 heal...Show More
A statistical methodology is proposed to rank several estimation methods of a relevant clinical parameter when no gold standard is available. Based on a regression without truth method, the proposed approach was applied to rank eight methods without using any a priori information regarding the reliability of each method and its degree of automation. It was only based on a prior concerning the stat...Show More
Current indications for aortic surgery are solely based on maximum aortic diameter and have proven to be nonreliable. There is an urgent need of pertinent information to aid physicians assess surgical risk-benefits and develop an adequate treatment for the patient as the morbidity and mortality risks for these interventions are considerably high. In this paper, we present an algorithm that semi-au...Show More
In this study, we developed a novel method for a fullyautomatic segmentation and quantification of myocardialinfarction from delay enhancement - magnetic resonanceimaging. Hyper-enhanced region corresponding to the infarctcore is separated from normal tissue via a Gaussian mixturemodel. Then, peri-infarct area is determined by spatial-weightedfuzzy clustering. No-reflow area inside the infarct cor...Show More
A statistical method is proposed to compare several estimates of a relevant clinical parameter when no gold standard is available. The method is illustrated by considering the left ventricle ejection fraction derived from cardiac magnetic resonance images and computed using seven approaches with different degrees of automation. The proposed method did not use any a priori regarding with the reliab...Show More
Magnetic resonance imaging (MRI) is well adapted for early detection of diseases such as aortic aneuryms or dissections. In this paper, we present a new Markovian method which evolves an active contour for 2D, 3D and 4D (3D + time) segmentation. As opposed to other Markovian contour-based methods, our approach considers an implicit contour as the boundary of a 2D region. The regions are modeled vi...Show More
Natural evolution of aortic disease is characterized by a diameter increase that can result in aortic dissection or rupture. Currently the evaluation of risk of rupture or dissection is based on the size of the aorta. However, this parameter is not always relevant and it appears necessary to define new parameters.Show More
The aortic compliance is defined as the relative change of aortic cross-sectional area divided by the change in arterial pressure. Magnetic resonance imaging (MRI) can be used to evaluate aortic compliance. A knowledge of the aortic contour is essential to determine the aortic area. To prevent important intra-and inter-observer variability, the aortic contours are detected automatically. This work...Show More
Magnetic resonance first-pass imaging of a bolus of contrast agent is well adapted to distinguish normal and hypoperfused areas of the myocardium. In most cases, the signal intensity-time curves in user defined regions of interest (ROI) are studied. As image acquisition is ECG-gated, the images are acquired at the same moment in the cardiac cycle, and the basic shape of the heart is similar from o...Show More
This article proposes a technique for tracking moving organs in medical imaging. It can be split into two stages. We first initialize a 1D-triangular mesh on the first image of the sequence. We distinguish different objects of interest by grouping together the triangles that make them up. Afterwards, we deform this mesh on the successive images in order to track each identified object. The trackin...Show More
The work presented here relates to a method for motion tracking in sequences of medical images. The purpose is to quantify the general motions and the local deformations of a beating heart during a cardiac cycle. In order to achieve this goal, we first tessellate the first image of the sequence into triangular patches. A Delaunay triangulation is applied to find the optimal set of triangles descri...Show More
The work reported here deals with movement tracking in sequences of medical images in order to quantify the general movements and deformations of the heart. For this purpose, we partition the first image into triangular patches in order that each object of the image corresponds to a set of triangles. Then, the nodes of the mesh are tracked across the image sequence giving a mesh which warps with t...Show More