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De-Shuang Huang - IEEE Xplore Author Profile

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Most of current ANN represents relations in the way of functional approximation. It is good for representing the numeric relations or ratios of things. However, it is not proper to represent logical relations in the form of ratio. Therefore, aiming for representing logical relations directly, we propose a new ANN model PLDNN (Probabilistic Logical Dynamical Neural Network). It defines new neurons ...Show More
In recent years, thanks to the efforts of individual scientists and research consortiums, a huge amount of chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) experimental data have been accumulated. Although several recent studies have demonstrated that a wealth of insights can be gained by integrative analysis of these data, owing to cost, time or sample material avai...Show More
In this paper, we propose a novel inverse-free iterative algorithm for efficiently solving the generalized eigenvalue problem in Canonical Correlation Analysis (CCA). Compared with the state-of-the-art approach of reformulating it as a regression problem, our method is more efficient and can find the exact solution to the original generalized eigenvalue problem under a milder condition. Numerical ...Show More
In this paper, we propose a novel approach for palmprint identification, which contains two interesting components. Firstly, we propose the directional representation for appearance based approaches. The new representation is robust to drastic illumination changes and preserves important discriminative information for classification. We then generate virtual samples to enlarge the training set to ...Show More
A modified version for semi-supervised learning algorithm with local and global consistency was proposed in this paper. The new method adds the label information, and adopts the geodesic distance rather than Euclidean distance as the measure of the difference between two data points when conducting calculation. In addition we add class prior knowledge. It was found that the effect of class prior k...Show More
ISOMAP is a manifold learning based algorithm for dimensionality reduction, which is successfully applied to data visualization. However, there exists such limitation in classical ISOMAP that the algorithm is sensitive to noises, especially outliers. So in this paper an extended ISOMAP algorithm is put forward to solve the problem of sensitivity. The proposed algorithm follows the method of classi...Show More
In this paper, an efficient feature extraction method named as Constrained Maximum Variance Mapping (CMVM) is developed for dimensionality reduction. The proposed algorithm can be viewed as a linear approximation of multi-manifolds based learning approach, which takes the local geometry and manifold labels into account. After the local scatters have been characterized, the proposed method focuses ...Show More
In this paper, a novel model of elliptical basis function neural networks (EBFNN) based on a hybrid optimization algorithm is proposed. Firstly, a geometry analytic algorithm is applied to construct the hyper-ellipsoid units of hidden layer of the EBFNN, i.e., an initial structure of the EBFNN, which is further pruned by the particle swarm optimization (PSO) algorithm. And the shape parameters of ...Show More
In this paper, an evolutionary modular neural network is proposed to solve multi-class problems with unbalanced training sets. The proposed model can transform an unbalanced classification problem into a set of symmetrical two-class problems, each of which can be solved by a single simple neural network. The experimental results show that the proposed method reduces time consumption for training a...Show More
This paper presents a novel multi-sub-swarm Particle Swarm Optimization (PSO) algorithm. The proposed algorithm can effectively imitate a natural ecosystem, in which the different sub-populations can compete with each other. After competing, the winner will continue to explore the original district, while the loser will be obliged to explore another district. Four benchmark multimodal functions of...Show More
It is a challenging task to diagnose tumor type precisely based on microarray data because the number of variables p (genes) is far larger than that of samples, n. Many independent component analysis (ICA) based models had been proposed to tackle the microarray data classification problem with great success. Although it was pointed out that different independent components (ICs) are of different b...Show More
Microarray data prediction is a hard task due to the small sample and high dimension property. This paper proposes a classifier fusion approch to solve this problem based on genetic algorithm (GA). In this fusion strategy, GA is applied to select proper feature subsets and weight value for the fusion of classifiers. The experimental results show that the proposed scheme can improve the prediction ...Show More
Identifying protein-protein interaction sites is crucial for understanding of the principles of biological systems and processes, as well as mutant design. This paper describes a novel method that can predict protein interaction sites in heterocomplexes using information of evolutionary conservation and spatial sequence profile. A predictor was generated to distinguish the interface residues from ...Show More
This paper analyzes the long-range interactions, which plays a fundamental and important role in many biologic fields, between residues in protein using principal component analysis (PCA). Firstly, one angular coordinate system of long-range interaction regions is constructed conveniently. Afterwards, a matrix of the angular values of residues can be analyzed by principal component analysis techni...Show More
In this paper, an online signature verification scheme based on spectrum analysis and Mahalanobis decision is proposed. We firstly divided signatures to a number of frames with variable widths according to the characteristics of the time sequences, and then employed the fast Fourier transformation (FFT) to extract the spectrum of signatures. The distance between the Fourier coefficient within the ...Show More
This paper presents a novel BP-based image retrieval (BPBIR) system, which is based on the observation that the images users need are often similar to a set of images with the same conception instead of one query image and the assumption that there is a nonlinear relationship between different features. If users aren't satisfied with the retrieved results, relevance feedback method is used to enha...Show More
In this paper a new method for recognition of 2D occluded shapes based on neural network using generalized differential evolution training algorithm is proposed. Firstly, a generalized differential evolution (GDE) algorithm is introduced. And this GDE algorithm is applied to train multilayer perceptron neural networks. Then a new shape feature, refer to as multiscale Fourier descriptors (MFDs) is ...Show More
In this paper, a nonlinear blind source separation system with post-nonlinear mixing; model, and an unsupervised learning algorithm for the parameters of this separating system are presented for blind inversion of Wiener system for single source. The proposed method firstly changes the deconvolution part of Wiener system into a special case of linear blind source separation (BSS). Then the nonline...Show More
This paper presents a novel method to solve the protein's three-dimensional structure prediction problem. It is a machine learning approach by integrating probabilistic neural network (PNN) with conformational energy function (CEF) based on chemico-physical knowledge of amino acids. In this method, firstly, the principal components are extracted from selected protein structures with lower sequence...Show More
In this paper, an algorithm using evolved regular expressions to characterize and predict human gene splice sites without any prior knowledge is described. In contrast to previous pattern-based approaches to the splice site detection problem, the patterns to be matched are unknown in advance and discovered using a supervised learning approach. We have used a genetic programming based system, PerlG...Show More
This paper proposes a new method that can predict the interactions between proteins intermediated by the protein-domain relations. We utilize the lazy expectation maximization (LEM) to compute an improved maximization likelihood estimation (MLE) model. The protein-domain relationships are extruded from Flam database and the combined data set of Uetz and Ito are used as the source of protein-protei...Show More
Support vector machines (SVMs) have been extensively used. However, it is known that SVMs face difficulty in solving large complex problems due to the intensive computation involved in their training algorithms, which are at least quadratic with respect to the number of training examples. This paper proposes a new, simple, and efficient network architecture which consists of several SVMs each trai...Show More
Microarray technology is a useful tool for monitoring the expressed levels of thousands of genes simultaneously. Recently, mixture modelling has been used to extract information from expressed genes. It utilizes two separate steps to estimate the number of classes and model parameters, respectively, which however may be time-consuming and fall into sub-optimal solutions. In this paper, we therefor...Show More
In this paper an efficient shape matching approach based on fuzzy discrete particle swarm optimization (FDPSO) is proposed. Based on fuzzy theory and PSO method, we applied this optimization method to a special combinatorial optimization problem: shape matching and recognition. Firstly, an original shape is approximated to a polygone and a shape representation of invariant attributes sequence is u...Show More