I. Introduction
Medical image segmentation plays a pivotal role in computer-aided diagnosis systems which are helpful in making clinical decisions. Segmenting a region of interest like an organ or lesion from a medical scan is critical as it contains details like the volume, shape and location of the region of interest. Automatic methods proposed for medical image segmentation help in aiding radiologists for making fast and labor-less annotations. Early medical segmentation methods were based on traditional pattern recognition techniques like statistical modeling and edge detection filters. Later, machine learning approaches using hand-crafted features based on the modality and type of segmentation task were developed. Recently, the state of the art methods for medical image segmentation for most modalities like magnetic resonance imaging (MRI), computed tomography (CT) and ultrasound (US) are based on deep learning. As convolutional neural networks (CNNs) extract data-specific features which are rich in quality and effective in representing the image and the region of interest, deep learning reduces the hassle of extracting manual features from the image.