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A Study on Hemodialyzer Membranes using Finite Element Analysis | IEEE Conference Publication | IEEE Xplore

A Study on Hemodialyzer Membranes using Finite Element Analysis


Abstract:

A high flux membrane is modelled for hemodialyzers. The function of high flux membrane is simulated to observe its role in overall toxin clearance and retaining necessary...Show More

Abstract:

A high flux membrane is modelled for hemodialyzers. The function of high flux membrane is simulated to observe its role in overall toxin clearance and retaining necessary solutes. In this study, hemodialyzer with a single membrane and multiple membranes are modelled using Finite element method. Toxin clearance is observed by varying different geometric parameters of the hollow fiber and velocity profile of the fluids such as blood and dialysate. Parameters are varied using combinations as per Taguchi algorithm for obtaining optimal results. Dialyzer with multiple membranes showed 20.97% better urea clearance than single membrane. Therefore, this design was further considered for the study of six solutes having different molecular weight ranging from low to high. Results shows that a multi layered membrane have better variance in toxin clearance than single layered hollow fiber membrane though loss of Albumin remains the same.
Date of Conference: 04 February 2020 - 09 April 2020
Date Added to IEEE Xplore: 16 June 2020
ISBN Information:
Conference Location: Dubai, United Arab Emirates

I. Introduction

Healthy kidneys are vital elements for survival. They keep the whole body in balance. When the kidneys fail to work the way it has to, it is known as kidney failure. It is asymptomatic and the patient will become aware of his/her situation only at the final stage of kidney failure known as End Stage Renal Disease (ESRD). It is a condition in which, the body fails to eliminate toxins and excess water. Retention of these toxins by the body are fatal.

References

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