An adaptive transcranial direct current stimulation (tDCS)

Traditional deep brain stimulation (DBS) has been proven to be effective in the treatment of neurological diseases, especially Parkinson's disease (PD), but the DBS system can be further optimized to maximize the therapeutic benefits. This paper presents a programmable and adaptive transcranial direct current stimulation, which is mainly composed of single-channel LFP monitoring, TDCS stimulation circuit and closed-loop control algorithm. Compared with the traditional deep brain stimulation for the treatment of Parkinson's disease, the adaptive transcranial direct current stimulation for Parkinson's disease (PD) has a better effect. The application of advanced technologies and treatment schemes is expected to achieve better clinical effects, save time for adjustment of parameters and avoid side effects.

I. Introduction

Transcranial direct current stimulation (tDCS) is a non-invasive technique that USES constant, low-intensity direct current (0-2ma) to regulate neuronal activity in the cerebral cortex. Increased or decreased excitability of neurons can lead to changes in brain function. Different from transcranial magnetic stimulation, tDCS does not cause neurons to discharge through supra threshold stimulation, but plays its role by regulating the activity of neural network [1]–[2]. In general, anode stimulation increases the excitability of neurons, while cathode stimulation inhibits them. TDCS has shown some therapeutic benefits in relieving and controlling pain, tinnitus, mental illness, depression, addiction, schizophrenia, anxiety, dementia, and enhancement of attention, learning, and memory.