1. Introduction
Image segmentation is a fundamental problem in biomedical image analysis. Recently, deep learning has significantly improved image segmentation accuracy on many problems. Most state-of-the-art deep learning segmentation models are based on the Encoder-Decoder architecture. The “encoder” is a typical deep convolutional network to encode hierarchical information into feature maps, while the “decoder” aims to make effective dense predictions using encoded features. The essential spirit of the Encoder-Decoder architecture is to first interpret the images and then predict the segmentation of the images based on the interpretation.