Characterization of self-assembled AuNPs film for optofluidic applications

To realize a sensitive and low cost optofluidic biosensor, we propose a localized surface plasmon resonance (LSPR) sensor chip based on supported gold nanoparticles (AuNPs). The AuNPs were generated by vacuum thermal evaporation and annealing process. Sample liquids with different concentration were utilized to characterize the sensitivity of the self-assembled AuNPs film. Important issue, one of the advantages of optofluidics can be coupling with LSPR sensors. The LSPR sensor integrated self-assembled continuous flow optofluidics with the flow rate of 50 μl/m showed the sensitivity along with its potential application of simple and low-cost fabrication.

I. Introduction

In the past few decades, interaction the noble metal nanostructured for biosensors application are mainly used for analysis of fluids, such as commercial products and including human physiological fluids for rapid early detection has been a challenge for decades through an optical sensing device [1] . Optical-based biosensors such as an optofluidic biosensor, nominally the research and technology area have been developed. Optofluidic system is one of the lab-on-a-chip system platform. Optofluidics is a new subdivision within photonics that attempts to integrate concepts from optics and microfluidics [2] . In addition, microfluidics is being applied to a large variety of sensing purpose such as biosensors, chemical sensor [3] . Optofluidic based chip biosensing systems have some remarkable reliability including quick response, low sample or low reagent usage, and great potential for achieving high sensitivity detection on compact single chip [4] . One of the advantages of optofluidics can be coupling with localized surface plasmon resonance (LSPR) sensors. It is an important issue for many analytical and biological applications [5] .