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In vivo photo-thermal optical coherence tomography of targeted mouse brain tumors using gold nanostars | IEEE Conference Publication | IEEE Xplore

In vivo photo-thermal optical coherence tomography of targeted mouse brain tumors using gold nanostars


Abstract:

We present structural and molecular-contrast imaging of mouse brain tumors using photo-thermal optical coherence tomography (PT-OCT) in vivo. Based on strong PT response ...Show More

Abstract:

We present structural and molecular-contrast imaging of mouse brain tumors using photo-thermal optical coherence tomography (PT-OCT) in vivo. Based on strong PT response of gold nanostars, we demonstrate clear visualization of brain cancer margins.
Date of Conference: 08-13 June 2014
Date Added to IEEE Xplore: 18 December 2014
Electronic ISBN:978-1-55752-999-2
Print ISSN: 2160-8989
Conference Location: San Jose, CA, USA

1. Introduction

The detection and resection of brain tumors is one of the main challenges in brain surgery. The brain tumors do not exhibit a clear boundary separating them from the adjacent normal brain tissues [1]. Conventional imaging techniques such as CT and MRI are typically employed to locate the cancer regions prior to the surgery. However, in operation, surgeons experience difficulty to locate the cancerous regions because of the discrepancies between the MRI/CT images and visual inspection. [2] Therefore, in situ imaging techniques that can provide a clear visualization of cancerous tissues during the operation would significantly help the current brain diagnosis and surgery.

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References

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