1. INTRODUCTION
In the plat-panel radiography image detectors, the thin film transistor (TFT) controls the flow of electronic signals of pho-toreceptors, in which the signals are multiplexed, amplified, and digitized by using multiple amplifiers and gate drivers. Since the amplifiers and gate drivers have irregular gains and offsets, acquired images show different gain and offset properties within an image depending on the amplifiers as pixel value differences. Furthermore, variation in photoreceptor size also results in a fixed pattern structure that has a gain component. Hence, the acquired image need to be offset and gain corrected [1], [2]. The offset correction is typically achieved by subtracting a dark image, which is acquired without exposure, from each subsequent exposure image. Conventional gain-correction approach is using an average of multiple uniformly illuminated images as a gain map to prevent the gain-corrected image from being contaminated by the noise of the gain map. The gain correction is important in evaluating the performance of the detector through the signal-to-noise ratio (SNR) and the detective quantum efficiency (DQE) [1], [3].