I. Introduction
There is a growing need to effectively and strategically manage large-scale infrastructure systems, such as air traffic systems, power grids, and environmental systems. These systems are typically subject to a wide range of uncertainties, which significantly complicate the evaluation and management of system performance. To give some examples, flow contingency management solutions are being developed for air traffic systems, which seek to automatically generate management plans over a 2–15 h lookahead time that are robust to weather uncertainties [26], [27]. In analogy, strategic resource scheduling and real-time surveillance/control algorithms are sought for the power grid, that are flexible to uncertainties in renewable generation and load, and robust to complex and uncertain fault events [12], [29]. As a step toward real-time management, techniques are needed for accurate yet computationally efficient evaluation/prediction of system performance over a range of parametric uncertainties. To address this need in broad infrastructure system applications, this paper develops a systematic method to effectively evaluate output statistics for systems with multiple uncertain input parameters.