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Multiple alignment of contact maps | IEEE Conference Publication | IEEE Xplore

Multiple alignment of contact maps


Abstract:

We show that multiple structure alignment (MStA) using contact maps is equivalent to the problem of finding a sample mean of contact maps. From this result, we derive a s...Show More

Abstract:

We show that multiple structure alignment (MStA) using contact maps is equivalent to the problem of finding a sample mean of contact maps. From this result, we derive a subgradient method for solving the MStA method. Experiments show that the proposed algorithm is a flexible alignment method that provides an excellent tradeoff between accuracy and speed.
Date of Conference: 14-19 June 2009
Date Added to IEEE Xplore: 31 July 2009
ISBN Information:

ISSN Information:

Conference Location: Atlanta, GA, USA
Citations are not available for this document.

I. Introduction

MULTIPLE STRUCTURE ALIGNMENT (MStA) is an essential task in structural bioinformatics, which is useful for protein structure classification, structure-based function prediction, and highlighting structurally conserved regions of functional significance. In addition, MStA can be used to gain deeper insights into the evolutionary history of proteins (see [6] and references therein). As a result, various MStA algorithms have been developed (see e.g. [3], [5], [6], [8], [10]).

Cites in Papers - |

Cites in Papers - IEEE (1)

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1.
Brijnesh Jain, Klaus Obermayer, "Consistent Estimator of Median and Mean Graph", 2010 20th International Conference on Pattern Recognition, pp.1032-1035, 2010.

Cites in Papers - Other Publishers (2)

1.
Brijnesh J. Jain, Klaus Obermayer, Structural, Syntactic, and Statistical Pattern Recognition, vol.6218, pp.690, 2010.
2.
Brijnesh J. Jain, Klaus Obermayer, Computer Analysis of Images and Patterns, vol.5702, pp.351, 2009.

References

References is not available for this document.