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Finite Element Modeling and Analysis of Hemodynamics in Middle Cerebral Artery | IEEE Conference Publication | IEEE Xplore

Finite Element Modeling and Analysis of Hemodynamics in Middle Cerebral Artery


Abstract:

This work presents a realistic finite element modeling approach for the analysis of hemodynamics in middle cerebral artery (MCA). In contrast to many other simplified mod...Show More

Abstract:

This work presents a realistic finite element modeling approach for the analysis of hemodynamics in middle cerebral artery (MCA). In contrast to many other simplified models, the proposed model considers a perforated domain at the end of the artery based on the theory of ramification, which is responsible to increase the pressure inside the artery through raising the hydraulic resistance. Thus, the proper modeling criterions and outlet boundary conditions helps to mimic the physiological scenario inside the artery. In particular, the systolic pressure of about 115 mmHg has been demonstrated inside the MCA keeping the blood flow velocity (57 cm/s) similar to that of physiological environment. Due to the perforated domain, the increment of the compactness by 112.2 times provides 85.12 % change of pressure than the truncated artery. Such proportional dependency of pressure on the compactness will be helpful to develop different patient-specific models. Therefore, the artery model with the perforated domain is suitable to analyze the hemodynamic parameters in medium and small artery system, as it has the potential to mimic physiological phenomenon.
Date of Conference: 07-09 December 2023
Date Added to IEEE Xplore: 13 February 2024
ISBN Information:
Conference Location: Khulna, Bangladesh
Dept. Of Biomedical Engineering, Khulna University of Engineering and Technology, Khulna, Bangladsh
Dept. Of Electronics and Communication Engineering, Khulna University of Engineering and Technology, Khulna, Bangladsh

I. Introduction

Cerebrovascular disease is one of the leading causes of death around the world. By 2021, it ranked as the fourth major life-threatening diseases among ten in Taiwan, which was responsible for the death of 12,182 people [1]. Various cerebrovascular diseases, such as thrombosis, artery stenosis, aneurysms, and vascular malformations, significantly affect the hemodynamic parameters (blood flow velocity, blood pressure, artery wall shear stress) in cerebral arteries. Arterial stenosis, for instance, obstructs blood flow, elevating pressure and velocity and eventually leading to vessel rupture and haemorrhagic stroke. The middle cerebral artery (MCA), which is originated from the internal carotid artery and is located at the base of the brain (cerebral peduncle), is one of the most susceptible regions where numerous cerebrovascular diseases manifest. Therefore, the hemodynamic analysis in MCA is of great interest to comprehend the mechanism and impact of such diseases.

Dept. Of Biomedical Engineering, Khulna University of Engineering and Technology, Khulna, Bangladsh
Dept. Of Electronics and Communication Engineering, Khulna University of Engineering and Technology, Khulna, Bangladsh

References

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