I. Introduction
The Internet of Things (IoT) is developing at a rapid growth and being integrated into several Information and Communication Technology (ICT) solutions. IoT technology is increasingly being incorporated into healthcare systems, and widely achieving a growing acceptance in different aspects of daily life [1]. Presently, an evolution from hospital-centered healthcare systems to hospital-home-balanced healthcare systems is in its early stages aiming to become someday home-centered healthcare systems [2]. But for such an evolution to develop further, new technologies, system architectures, and computing paradigms are required. And, with the development of this evolution towards Learning Healthcare Systems (LHS), new challenges occur in system reliability, interoperability, low latency response, energy efficiency, mobility, security, and privacy become requirements to fulfill. This extension of healthcare boundaries outside the hospital settings, into the consumer domain, aims for the early detection and prevention of health deterioration and permitting consumers to live independently at home, allowing people with acute diseases and at-risk populations as senior adults to be continuously monitored and guided by healthcare providers [3], wardens or family members, and to receive advice on their healthcare.