I. Background
The generation of a digital fingerprint (or simulated model) encourages developments to diagnose healthcare problems, processes, and/or services. This type of model can investigate, forecast, and augment all operations before implementing it in actual-world conditions [1], [2]. The simulation of data using a closed loop is transferred back to the physical object to regulate the operations and improve the device’s performance [3]. This bidirectional recording between cyber–physical space (CPS) and simulated space is known as the cyber twin (CT). CT is the digital depiction of the objects or humans in the cybernetic world and works as the simulated network [4], [5]. To start the operation of physical resources, CTs assemble and assimilate data from numerous sources comprising wearable healthcare sensors, historical data of patients attained from the activities of daily living, and domain information to produce inclusive data in the form of prototypes, simulations, duplications, or behavioral analytics [6], [7]. During the clinical diagnosis, the CTs function synchronously with their corresponding physical objects with the basic objective to locate and find out the data discrepancies between the physical and simulated objects. The data discrepancies between the physical and simulated objects require improved standardization and testing policies that develop CT models corresponding to the physical objects to support precise measurement, forecast, and optimization of the diagnosis procedures for human in the loop [8].