Quantitative reconstruction of cone beam X-ray computed tomography (CT) datasets requires accurate modeling of scatter, beam-hardening, beam profile, and detector response. Typically, commercial imaging systems use fast empirical corrections that are designed to reduce visible artifacts due to incomplete modeling of the image formation process. In contrast, Monte Carlo (MC) methods are much more a...Show More
The accurate delivery of external beam radiation therapy is often facilitated through the implantation of radio-opaque fiducial markers (seeds). Before the delivery of each treatment fraction, seed positions can be determined via volumetric imaging. By registering these seed locations with the corresponding locations in the previously acquired treatment planning CT, it is possible to adjust the pa...Show More