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Gabriele Cevenini - IEEE Xplore Author Profile

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We present a technique to estimate the pleural pressure combining the information provided by the central venous pressure (CVP) and electrocardiographic signals (ECG) for respiratory system monitoring. We discuss the characterization of the proposed measurement method with theoretical modeling, numerical analysis, and experiments based on signals acquired from intensive care unit patients. The res...Show More
We present a measurement system to estimate the trans-pulmonary pressure combining the information provided by the central venous pressure and the electrocardiographic signals. We discuss the characterization of the measurement system with theoretical modeling, numerical analysis and experiments based on signals acquired from intensive care unit patients. The results confirm the validity of the pr...Show More
Spitzoid melanocytic skin lesions (MSL) include Spitz nevi (SN) and spitzoid melanomas (SM). A third rare subset was described, atypical spitz tumors (AST), that share overlapping histologic features of SN and SM. Being difficult to diagnose lesions, both with dermoscopy and histology, there is considerable uncertainty regarding their biological potential. We aimed to investigate if digital dermos...Show More
Three scoring systems were considered and described for dermatological applications in which malignant and benign skin lesions have to be recognized: two models are derived from logistic regression and naïve Bayes rule by rounding model parameters to their nearest integer values; the third approach defines the scoring system by a direct stepwise adding of the most significant binary risk factors. ...Show More
A non-linear lumped-parameter model of the tracheobronchial tree has been recently proposed to simulate expiratory flow limitation (EFL) in mechanical ventilation. The model is based on Weibel's symmetrical description of lung anatomy subdivided into 24 generations, where the first 17 generations correspond to conductive airways and the last 7 generations belong to the respiratory zone. Thanks to ...Show More
A two-layer feedforward neural network for classifying intensive care patients as normal or at risk for severe cardiorespiratory disorders was designed and compared with the best, previously investigated, Bayesian classifier of similar complexity. At three distinct observation times soon after heart surgery, the three variables most effective in separating the two classes were measured and used to...Show More
A multiple linear stepwise regression approach was applied to respiratory data from intensive care patients. The influence of different nonlinear viscoelastic properties on the prediction of pressure at the airway opening taken as dependent variable was studied by entering and removing potential predictive variables. These variables were derived from measured ventilatory flow data so as to quantit...Show More
The first-order model of breathing mechanics is widely used in clinical practice to assess the viscoelastic properties of the respiratory system. Although simple, this model takes the predominant features of the pressure-flow relationship into account but gives highly systematic residuals between measured and model-predicted variables. To achieve a better fit of the entire data set, an approach hy...Show More
Two new algorithms with reduced sensitivity to the changing environment are applied to tracking arterial circulation parameters. They are variants of the Least-Squares (LS) algorithm with Variable Forgetting factor (LSVF), and of the Constant Forgetting factor-Covariance Modification (CFCM) LS algorithm, devised to overcome their main practical deficiencies related to noise level sensitivity and t...Show More
The problem of tracking changes in viscoelastic properties of the systemic arterial bed is considered, and a recursive estimation procedure, belonging to the class of output-error algorithms with adjustable compensator, is developed and discussed. By means of computer simulation, suitable values are determined for the key design variable which controls the tradeoff between the tracking ability and...Show More
The problem of choosing parametric descriptions of the systematic vascular bed suitable for monitoring beat-to-beat changes in peripheral vascular properties is considered. Three simple models with two, three, and five elements are compared, essentially exploiting the Akaike information criterion combined with reasonable requirements for estimate accuracy. Analysis of pressure data, which are eith...
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A recursive identification algorithm with a constant forgetting factor is applied to online identification of the mechanical properties of the respiratory system. The well-known two-parameter model, accounting for pulmonary compliance and resistance, is adopted to characterize breathing mechanics. The algorithm is first tested by using flow and pressure data measured on mechanically ventilated dog...
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