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Differential SHH and IHH expression during osteogenesis induced by Dexamethasone in rat bone marrow mesenchymal cells
Xiaoli Ma;Shanshan Zu;Yanfei Jia;Yan Zheng;Shuyi Han;Hua Liu;Dongjie Xiao;Yunshan Wang;Xueping Zhang;Haiji Sun;Liguo An
2011 4th International Conference on Biomedical Engineering and Informatics (BMEI)
Year: 2011 | Conference Paper |
Hedgehog signaling pathway is an important signal pathway, which regulates the development of variety of tissues and organs in the embryonic stage. It also plays an important role in osteogenesis. However, there are few data recording the role of Hedgehog signaling molecules in osteogenic differentiation of bone marrow mesenchymal stem cells in vitro. Dexamethasone (DEX), a synthetic and widely us...Show More
CHRNA5 variants related to nicotine sensitivity in lung cancer in vitro
Haiji Sun;Liguo An;Yun Zhao;Xiaoli Ma;Yunshan Wang;Yanfei Jia;Yan Zheng;Dongjie Xiao
2010 3rd International Conference on Biomedical Engineering and Informatics
Year: 2010 | Conference Paper |
Cited by: Papers (7)
Nicotine, the chemical compound which causes cigarette addiction, could be responsible for some lung cancers. Evidence for genetic influence on smoking behavior and nicotine dependence has prompted a search for susceptibility genes. Furthermore, assessing the impact of sequence variants on smoking-related diseases is important to public health. Recently, the locus containing two genes encoding nic...Show More
The Enhancement of Drug Sensitivity of Human AFP-Producing Gastric Carcinoma Cell Line FU97 to Arsenic Trioxide Using AFP as Targeting siRNA
2009 3rd International Conference on Bioinformatics and Biomedical Engineering
Year: 2009 | Conference Paper |
AFP-producing gastric carcinoma(APGC) are known to have a poorer prognosis and to show a higher incidence of liver metastasis than ordinary gastric carcinoma. Therefore, surgical resection, chemotherapy or radiotherapy is usually not satisfactory. In recent years, effects of arsenic trioxide (As2O3) on cell proliferation and induced apoptosis of solid tumors have been widely studied, while little ...Show More
Expression of Human Differentiated Embryo-Chondrocyte Expressed Gene 1 in Gastric Carcinoma and Its Correlation with STAT3
Yan Zheng;Yanfei Jia;Binbin Li;Min Wang;Dongjie Xiao;Yunshan Wang
2009 3rd International Conference on Bioinformatics and Biomedical Engineering
Year: 2009 | Conference Paper |
DEC1, also known as SHARP-2 or Stral3, is an important molecule in embryonic differentiation and a bHLH type transcriptional regulator. It has recently been identified to be abundantly expressed in several human tumors and might play an important role in tumor development. But its expression in gastric carcinoma is unknown. In this study we show that DEC1 was frequently expressed in six gastric ca...Show More
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