Roberto Lavarello - IEEE Xplore Author Profile
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Roberto Lavarello

Also published under: Roberto J. Lavarello, R. Lavarello, R. J. Lavarello

Publications
85
Citations
551
Publications by Year
20062025
Co-Authors:
Show All Co-Authors (111)
Image of author Roberto Lavarello

Roberto Lavarello

Also published under: Roberto J. Lavarello, R. Lavarello, R. J. Lavarello

Affiliation

Departamento de Ingeniería
Laboratorio de Imágenes Médicas
Pontificia Universidad Católica del Perú, Lima, Perú

Publication Topics

Biography

Roberto J. Lavarello (Senior Member, IEEE) received the B.Sc. degree in electronics engineering from the Pontificia Universidad Católica del Perú, in 2000, and the M.Sc. and Ph.D. degrees in electrical and computer engineering from the University of Illinois at Urbana–Champaign, in 2005 and 2009, respectively. He is currently a Full Professor with the Department of Engineering, Pontificia Universidad Católica del Perú, and the Director of the Medical Imaging Laboratory. His research interests include reconstruction and processing of images for the non-invasive assessment of pathological conditions. He is a Former Fulbright Scholarship Recipient. He is a member of the IEEE EMBS Technical Committee on Biomedical Imaging and Image Processing, ...
Publications
85
Citations
551
Publications by Year
20062025
Co-Authors:
Show All Co-Authors (111)
Author's Published Works

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Spatially Weighted Fidelity and Regularization Terms for Attenuation Imaging

Sebastian Merino;Roberto Lavarello

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Year: 2025 | Volume: 72, Issue: 3 | Journal Article |
Quantitative ultrasound (QUS) holds promise in enhancing diagnostic accuracy. For attenuation imaging, the regularized spectral log difference (RSLD) can generate accurate local attenuation maps. However, the performance of the method degrades when significant changes in backscatter amplitude occur. Variations in the technique were introduced involving a weighted approach to backscatter regulariza...Show More

Spatially Weighted Fidelity and Regularization Terms for Attenuation Imaging

Sebastian Merino;Roberto Lavarello

Year: 2025 | Volume: 72, Issue: 3 | Journal Article |

Robustness Assessment of End-to-End Deep Ultrasound Beamformers Using Adversarial Perturbations

Itamar Salazar-Reque;Roberto Lavarello

2024 IEEE UFFC Latin America Ultrasonics Symposium (LAUS)
Year: 2024 | Conference Paper |
Cited by: Papers (1)
Ultrasound beamformers play a critical role in medical imaging, and understanding their robustness under worst-case scenarios is essential for reliable performance. This study investigates the adversarial robustness of two beamformers that used deep neural networks (DNN) trained in an end-to-end fashion by producing B-mode reconstructions directly from raw ultrasound channel data. Results reveal c...Show More

Robustness Assessment of End-to-End Deep Ultrasound Beamformers Using Adversarial Perturbations

Itamar Salazar-Reque;Roberto Lavarello

Year: 2024 | Conference Paper |

Reducing the Degrees of Freedom for Simultaneous Estimation of Ultrasonic Attenuation and Backscatter Coefficients: Application to Liver Steatosis Detection

José Timaná;Hector Chahuara;Lokesh Basavarajappa;Adrian Basarab;Kenneth Hoyt;Roberto Lavarello

2023 IEEE International Ultrasonics Symposium (IUS)
Year: 2023 | Conference Paper |
Cited by: Papers (1)
Liver steatosis, a type of fatty liver disease, has been gaining significant attention in the medical field due to its global prevalence. Currently, large-scale evaluations of liver steatosis are hindered by the variability of the available non-invasive imaging tools. While conventional ultrasound often serves as the primary imaging modality for liver assessments, its accuracy is limited by its qu...Show More

Reducing the Degrees of Freedom for Simultaneous Estimation of Ultrasonic Attenuation and Backscatter Coefficients: Application to Liver Steatosis Detection

José Timaná;Hector Chahuara;Lokesh Basavarajappa;Adrian Basarab;Kenneth Hoyt;Roberto Lavarello

Year: 2023 | Conference Paper |

Multifrequency Joint Reconstruction of Ultrasonic Attenuation Images

Edmundo A. Miranda;Adrian Basarab;Roberto Lavarello

2023 IEEE International Ultrasonics Symposium (IUS)
Year: 2023 | Conference Paper |
Cited by: Papers (2)
The estimation of attenuation coefficient slope (ACS) using the Spectral Log Difference (SLD) technique has presented high variability, leading to the use of regularization approaches. To address this issue, a previous study proposed the isolated denoising of the spectral log ratios at each frequency (TVSLD). In this study, we present a multifrequency joint method (WTNV-SLD) that leverages spatial...Show More

Multifrequency Joint Reconstruction of Ultrasonic Attenuation Images

Edmundo A. Miranda;Adrian Basarab;Roberto Lavarello

Year: 2023 | Conference Paper |

Depletion of backscattered fundamental band signal for nonlinearity parameter imaging

Andres Coila;Adriana Romero;Edmundo A. Miranda;Michael L. Oelze;Roberto Lavarello

2023 IEEE International Ultrasonics Symposium (IUS)
Year: 2023 | Conference Paper |
Cited by: Papers (5)
The estimation of the nonlinearity parameter (B/A) has potential to be used in the diagnosis of conditions such as liver steatosis. Recently, a pulse-echo method to estimate B/A using: a dual-energy approach, one reference phantom, and the approximation of the 2nd harmonic in terms of envelopes of fundamental band of RF data was presented. However, the performance of this method degrades when the ...Show More

Depletion of backscattered fundamental band signal for nonlinearity parameter imaging

Andres Coila;Adriana Romero;Edmundo A. Miranda;Michael L. Oelze;Roberto Lavarello

Year: 2023 | Conference Paper |

Robustness of ultrasound deep beamformers using low-energy adversarial perturbations

Itamar Salazar-Reque;Andrés Coila;Roberto Lavarello

2023 IEEE International Ultrasonics Symposium (IUS)
Year: 2023 | Conference Paper |
Cited by: Papers (2)
As the use of ultrasound beamformers based on deep neural networks (DNNs) continues to gain popularity, it becomes increasingly important to assess their robustness. Traditional model-based beamformers are typically evaluated by studying factors such as sound speed variations, off-axis clutter, and other variables that challenge the underlying model. However, these conventional evaluation methods ...Show More

Robustness of ultrasound deep beamformers using low-energy adversarial perturbations

Itamar Salazar-Reque;Andrés Coila;Roberto Lavarello

Year: 2023 | Conference Paper |

Total Nuclear Variation Spectral Log Difference for Ultrasonic Attenuation Images

Edmundo A. Miranda;Adrian Basarab;Roberto Lavarello

2023 IEEE 20th International Symposium on Biomedical Imaging (ISBI)
Year: 2023 | Conference Paper |
Cited by: Papers (1)
Quantitative Ultrasound (QUS) is a non-invasive imaging modality that characterizes tissues numerically. A well-known QUS parameter is the attenuation coefficient slope (ACS). A previous work proposed a regularized spectral log difference method (RSLD) to estimate the ACS, yet the ACS and the backscatter component were computed as independent parameters using a single channel total variation with ...Show More

Total Nuclear Variation Spectral Log Difference for Ultrasonic Attenuation Images

Edmundo A. Miranda;Adrian Basarab;Roberto Lavarello

Year: 2023 | Conference Paper |

H-scan ultrasound imaging for the classification of thyroid tumors

Mawia Khairalseed;Rosa Laimes;Joseph Pinto;Jorge Guerrero;Himelda Chavez;Claudia Salazar;Gary R. Ge;Roberto J. Lavarello;Kenneth Hoyt

2022 IEEE International Ultrasonics Symposium (IUS)
Year: 2022 | Conference Paper |
Cited by: Papers (2)
H-scan ultrasound (US) imaging is a high-resolution soft tissue characterization technique. It is a matched filter approach derived from analysis of scattering from incident pulses in the general form of nth-order Gaussian-weighted Hermite polynomial functions (GHn). The purpose of this study was to evaluate the potential of H-scan US imaging to distinguish scatterer distributions of biopsy-confir...Show More

H-scan ultrasound imaging for the classification of thyroid tumors

Mawia Khairalseed;Rosa Laimes;Joseph Pinto;Jorge Guerrero;Himelda Chavez;Claudia Salazar;Gary R. Ge;Roberto J. Lavarello;Kenneth Hoyt

Year: 2022 | Conference Paper |

Feasibility of Attenuation Coefficient and Envelope Signal-to-Noise Ratio Estimation for Tissue Characterization of Liver Steatosis

José Timaná;Hector Chahuara;Lokesh Basavaraiappa;Adrian Basarab;Kenneth Hoyt;Roberto Lavarello

2022 IEEE International Ultrasonics Symposium (IUS)
Year: 2022 | Conference Paper |
Cited by: Papers (1)
Nonalcoholic fatty liver disease (NAFLD) has become the most common cause of chronic liver disease worldwide. In addition, conducting large-scale screening studies is still challenging due to the absence of reliable and affordable noninvasive tools for NAFLD staging. Conventional ultrasound is commonly the preferred first imaging modality used to evaluate liver steatosis. However, it is mainly a q...Show More

Feasibility of Attenuation Coefficient and Envelope Signal-to-Noise Ratio Estimation for Tissue Characterization of Liver Steatosis

José Timaná;Hector Chahuara;Lokesh Basavaraiappa;Adrian Basarab;Kenneth Hoyt;Roberto Lavarello

Year: 2022 | Conference Paper |

Attenuation coefficient imaging using regularization by denoising

Anthony Carrera;Adrian Basarab;Roberto Lavarello

2022 IEEE International Ultrasonics Symposium (IUS)
Year: 2022 | Conference Paper |
The attenuation coefficient (AC) is parameter used in quantitative ultrasound that allows the characterization of different tissue types. The regularized spectral log difference (RSLD) method is a technique that uses a regularization step based on total variation in order to extend the trade-off between the estimation variance and spatial resolution. However, the RSLD method consider only piecewis...Show More

Attenuation coefficient imaging using regularization by denoising

Anthony Carrera;Adrian Basarab;Roberto Lavarello

Year: 2022 | Conference Paper |

Simultaneous Imaging of Ultrasonic Backscatter and Attenuation Coefficients for Liver Steatosis Detection in a Murine Animal Model

José Timaná;Hector Chahuara;Lokesh Basavarajappa;Adrian Basarab;Kenneth Hoyt;Roberto Lavarello

2022 IEEE 19th International Symposium on Biomedical Imaging (ISBI)
Year: 2022 | Conference Paper |
Cited by: Papers (3)
Non-alcoholic fatty liver disease (NAFLD) is one of the most prevalent chronic liver diseases. While early diagnosis is the most effective course of action, NAFLD diagnosis procedures are still limited since they are invasive and have a heavy component of subjectivity. In this paper, we present an approach based on Quantitative ultrasound (QUS) and Support Vector Machines (SVM) to detect liver ste...Show More

Simultaneous Imaging of Ultrasonic Backscatter and Attenuation Coefficients for Liver Steatosis Detection in a Murine Animal Model

José Timaná;Hector Chahuara;Lokesh Basavarajappa;Adrian Basarab;Kenneth Hoyt;Roberto Lavarello

Year: 2022 | Conference Paper |

Viscoelastic Characterization of in vivo Human Dermis Using High-Frequency Ultrasonic Crawling Wave Elastography

Ana C. Saavedra;Junior Arroyo;Gilmer Flores;Fernando Zvietcovich;Benjamin Castaneda;Roberto J. Lavarello

IEEE Access
Year: 2022 | Volume: 10 | Journal Article |
Cited by: Papers (4)
High-frequency (center frequency of 18MHz) ultrasound was combined with crawling wave elastography to characterize skin viscoelastic properties in two anatomical sites (i.e., thigh and forearm) in humans in the range of 200–400 Hz. The Voigt model was used to obtain shear elasticity and shear viscosity estimates. The forearm’s mean shear elasticity and shear viscosity were 6 kPa and 5.5 Pa.s, resp...Show More

Viscoelastic Characterization of in vivo Human Dermis Using High-Frequency Ultrasonic Crawling Wave Elastography

Ana C. Saavedra;Junior Arroyo;Gilmer Flores;Fernando Zvietcovich;Benjamin Castaneda;Roberto J. Lavarello

Year: 2022 | Volume: 10 | Journal Article |

Classification of thyroid nodules in H-scan ultrasound images using texture and prinicipal component analysis

Mawia Khairalseed;Rosa Laimes;Joseph Pinto;Jorge Guerrero;Himelda Chavez;Claudia Salazar;Gary R. Ge;Kevin J. Parker;Roberto J. Lavarello;Kenneth Hoyt

2021 IEEE UFFC Latin America Ultrasonics Symposium (LAUS)
Year: 2021 | Conference Paper |
Cited by: Papers (5)
H-scan ultrasound (US) imaging is a new tissue classification approach that depicts the relative size of scattering objects. The purpose of this study was to assess the ability of in vivo H-scan US imaging to discriminate benign from malignant thyroid nodules in human subjects. Image data was acquired using a SonixTouch US scanner (Analogic Ultrasound) equipped with an L14-5 transducer. To generat...Show More

Classification of thyroid nodules in H-scan ultrasound images using texture and prinicipal component analysis

Mawia Khairalseed;Rosa Laimes;Joseph Pinto;Jorge Guerrero;Himelda Chavez;Claudia Salazar;Gary R. Ge;Kevin J. Parker;Roberto J. Lavarello;Kenneth Hoyt

Year: 2021 | Conference Paper |

Spectral-based Ultrasonic Characterization of Renal Allografts in vivo

E. Acosta;C. Amador;S. Aristízabal;M. L. Montero;M. W. Urban;R. J. Lavarello

2021 Global Medical Engineering Physics Exchanges/Pan American Health Care Exchanges (GMEPE/PAHCE)
Year: 2021 | Conference Paper |
Kidney transplantation is the preferred long-term treatment modality for patients with end-stage renal disease as it confers improved survival and quality of life devoid of dialysis constraints. However, graft loss is still a concern in transplant recipients, necessitating close monitoring. The estimated glomerular filtration rate (eGFR) is often used as a surrogate marker of kidney function. Many...Show More

Spectral-based Ultrasonic Characterization of Renal Allografts in vivo

E. Acosta;C. Amador;S. Aristízabal;M. L. Montero;M. W. Urban;R. J. Lavarello

Year: 2021 | Conference Paper |

Regularized framework for simultaneous estimation of ultrasonic attenuation and backscatter coefficients

Hector Chahuara;Adrian Basarab;Roberto Lavarello

2020 IEEE International Ultrasonics Symposium (IUS)
Year: 2020 | Conference Paper |
Cited by: Papers (10)
Quantitative ultrasound (QUS) is a set of techniques for tissue characterization which allows to model tissue properties, such as ultrasonic attenuation and backscatter coefficients. Nevertheless, the challenge of QUS parameters estimation still remains as the trade-off between estimates variance and spatial resolution limits the applicability of the estimations. This work aims at providing an eff...Show More

Regularized framework for simultaneous estimation of ultrasonic attenuation and backscatter coefficients

Hector Chahuara;Adrian Basarab;Roberto Lavarello

Year: 2020 | Conference Paper |

Multi-wave dermis characterization using attenuation coefficient and shear wave speed estimates in vivo

Ana Cecilia Saavedra;Benjamin Castaneda;Roberto J. Lavarello

2019 IEEE International Ultrasonics Symposium (IUS)
Year: 2019 | Conference Paper |
Skin characterization is of importance for disease diagnosis and treatment follow-up. In particular, estimation of the biomechanical properties is useful for wound healing monitoring. This study proposes and validates for the first time the use of multi-wave quantitative ultrasound (MWQUS) as a skin characterization tool via the estimation of attenuation coefficient slope (ACS) and shear wave spee...Show More

Multi-wave dermis characterization using attenuation coefficient and shear wave speed estimates in vivo

Ana Cecilia Saavedra;Benjamin Castaneda;Roberto J. Lavarello

Year: 2019 | Conference Paper |

Enhanced Second Harmonic Imaging Using a Pulse Compression Technique Combined with Ultrasound Pulse Inversion

Yanis Mehdi Benane;Denis Bujoreanu;Roberto Lavarello;Adeline Bernard;Christian Cachard;Olivier Basset

2018 IEEE International Ultrasonics Symposium (IUS)
Year: 2018 | Conference Paper |
Pulse Inversion (PI) is a transmission technique used for harmonic imaging. By transmitting two phase inverted signals, which allow cancelling out the fundamental component, PI is able to achieve better image quality thanks to the reduced clutter/reverberation and to the improved bandwidth of the second harmonic. Here, a technique based on Resolution Enhancement Compression (REC) that improves the...Show More

Enhanced Second Harmonic Imaging Using a Pulse Compression Technique Combined with Ultrasound Pulse Inversion

Yanis Mehdi Benane;Denis Bujoreanu;Roberto Lavarello;Adeline Bernard;Christian Cachard;Olivier Basset

Year: 2018 | Conference Paper |

In vivo Attenuation Coefficient Estimation in the Healthy Forearm and Thigh Human Dermis

Ana Cecilia Saavedra;Andres Coila;Junior Arroyo;Benjamin Castaneda;Roberto J. Lavarello

2018 IEEE International Ultrasonics Symposium (IUS)
Year: 2018 | Conference Paper |
Cited by: Papers (2)
Few studies of in vivo normal human dermis characterization have been reported. In this study, the regularized spectral-log difference (RSLD) method was used for the estimation of the attenuation coefficient slope (ACS) in the forearm and thigh dermis with the objective of complementing previous studies on characterization of the forearm dermis and exploring the variations of ACS at different anat...Show More

In vivo Attenuation Coefficient Estimation in the Healthy Forearm and Thigh Human Dermis

Ana Cecilia Saavedra;Andres Coila;Junior Arroyo;Benjamin Castaneda;Roberto J. Lavarello

Year: 2018 | Conference Paper |

In Vivo Diagnosis of Metastasis in Cervical Lymph Nodes Using Backscatter Coefficients

Gloria Valenzuela;Rosa Laimes;Imelda Chavez;Claudia Salazar;Eduardo Gonzales Bellido;Indira Tirado;Joseph Pinto;Jorge Guerrero;Roberto J. Lavarello

2018 IEEE International Ultrasonics Symposium (IUS)
Year: 2018 | Conference Paper |
Cited by: Papers (2)
Lymph nodes characterization plays an important role in cancer staging and detecting local or distant recurrences. Previous studies have demonstrated the usefulness of ultrasound backscatter coefficients (BSCs) at high frequencies (16.4 - 33.6 MHz) for detecting micro-metastasis of colorectal, gastric and breast cancers in lymph nodes. However, these studies were conducted ex vivo. In this work, t...Show More

In Vivo Diagnosis of Metastasis in Cervical Lymph Nodes Using Backscatter Coefficients

Gloria Valenzuela;Rosa Laimes;Imelda Chavez;Claudia Salazar;Eduardo Gonzales Bellido;Indira Tirado;Joseph Pinto;Jorge Guerrero;Roberto J. Lavarello

Year: 2018 | Conference Paper |

Analysis of the Accuracy and Precision of the Least Square Fitting Method for Simultaneous Estimation of Backscatter and Attenuation Coefficients

Johan Polack;Andres Coila;Michael Oelze;Roberto Lavarello

2018 IEEE International Ultrasonics Symposium (IUS)
Year: 2018 | Conference Paper |
Quantitative ultrasound parameters such as backscatter and attenuation coefficients can be used to characterize tissues along with B-mode image ultrasound. However, these coefficients must be accurately found, and can be hard to measure. Simultaneous estimation of both backscatter coefficient and the total attenuation reduces the necessity of rely on previous studies to accurate know the attenuati...Show More

Analysis of the Accuracy and Precision of the Least Square Fitting Method for Simultaneous Estimation of Backscatter and Attenuation Coefficients

Johan Polack;Andres Coila;Michael Oelze;Roberto Lavarello

Year: 2018 | Conference Paper |

In vivo estimation of the Young’s modulus in normal human dermis

Ana Cecilia Saavedra;Junior Arroyo;Fernando Zvietcovich;Roberto J. Lavarello;Benjamin Castaneda

2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Year: 2018 | Conference Paper |
Cited by: Papers (6)
Skin elastic properties change during a cutaneous disorder or in the aging process. Deep knowledge of skin layers helps monitoring and diagnosing structural changes. High frequency ultrasound (HF-US) has been recently introduced to diagnose and evaluate some dermatological disorders in the clinical practice. US elastography adds elasticity information of the analyzed tissue. In particular, harmoni...Show More

In vivo estimation of the Young’s modulus in normal human dermis

Ana Cecilia Saavedra;Junior Arroyo;Fernando Zvietcovich;Roberto J. Lavarello;Benjamin Castaneda

Year: 2018 | Conference Paper |

An Attenuation Adapted Pulse Compression Technique to Enhance the Bandwidth and the Resolution Using Ultrafast Ultrasound Imaging

Yanis Mehdi Benane;Denis Bujoreanu;Roberto Lavarello;Christian Cachard;Olivier Basset

2018 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP)
Year: 2018 | Conference Paper |
Cited by: Papers (3)
Recent studies suggest that Resolution Enhancement Compression (REC) can provide significant improvements in terms of imaging quality over Classical Pulsed (CP) ultrasonic imaging techniques, by employing frequency and amplitude modulated transmitted signals. However the performance of coded excitations methods degrades drastically deeper into the tissue where the attenuation effects become more s...Show More

An Attenuation Adapted Pulse Compression Technique to Enhance the Bandwidth and the Resolution Using Ultrafast Ultrasound Imaging

Yanis Mehdi Benane;Denis Bujoreanu;Roberto Lavarello;Christian Cachard;Olivier Basset

Year: 2018 | Conference Paper |

Recent developments in spectral-based ultrasonic tissue characterization

Andres Coila;Gabriela Torres;Julien Rouyer;Sara Aristizabal;Matthew Urban;Roberto Lavarello

2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018)
Year: 2018 | Conference Paper |
Cited by: Papers (2)
Echographic imaging depicts anatomical structure by displaying the magnitude of the envelope-detected backscattered echoes. However, ultrasonic radiofrequency data contains a richer information content that can be exploited for constructing images of intrinsic tissue properties. In particular, spectral-based ultrasonic tissue characterization techniques allow imaging parameters such as the backsca...Show More

Recent developments in spectral-based ultrasonic tissue characterization

Andres Coila;Gabriela Torres;Julien Rouyer;Sara Aristizabal;Matthew Urban;Roberto Lavarello

Year: 2018 | Conference Paper |

Experimental Implementation of a Pulse Compression Technique Using Coherent Plane-Wave Compounding

Yanis Mehdi Benane;Denis Bujoreanu;Roberto J. Lavarello;François Varray;Jean-Michel Escoffre;Anthony Novell;Christian Cachard;Olivier Basset

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Year: 2018 | Volume: 65, Issue: 6 | Journal Article |
Cited by: Papers (10)
The axial resolution of an ultrasound imaging system is inversely proportional to the bandwidth of the emitted signal. When conventional pulsing (CP) is used, the impulse response of the transducer and the excitation signal determine together the shape of the emitted pulse and its bandwidth. A way to increase the ultrasound image resolution is to increase the transducer's limited passband. The res...Show More

Experimental Implementation of a Pulse Compression Technique Using Coherent Plane-Wave Compounding

Yanis Mehdi Benane;Denis Bujoreanu;Roberto J. Lavarello;François Varray;Jean-Michel Escoffre;Anthony Novell;Christian Cachard;Olivier Basset

Year: 2018 | Volume: 65, Issue: 6 | Journal Article |

Regularized Spectral Log Difference Technique for Ultrasonic Attenuation Imaging

Andres L. Coila;Roberto Lavarello

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
Year: 2018 | Volume: 65, Issue: 3 | Journal Article |
Cited by: Papers (69)
The attenuation coefficient slope (ACS) has the potential to be used for tissue characterization and as a diagnostic ultrasound tool, hence complementing B-mode images. The ACS can be valuable for the estimation of other ultrasound parameters such as the backscatter coefficient. There is a well-known tradeoff between the precision of the estimated ACS values and the data block size used in the spe...Show More

Regularized Spectral Log Difference Technique for Ultrasonic Attenuation Imaging

Andres L. Coila;Roberto Lavarello

Year: 2018 | Volume: 65, Issue: 3 | Journal Article |

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