Acoustofluidic Based Wireless Micropump for Portable Drug Delivery Applications

In this study, an acoustofluidic based wireless micropump for drug delivery was proposed and fabricated. The key actuator of this micropump is a small gigahertz piezoelectric resonator, which could induce strong fluidic streaming at low applied power. This acoustofluidic micropump has stable and accurate dosage resolution (7.0 μL), and sufficient flow rate (1.34 mL/min). The miniaturized size and wireless controlled operation prove it as a portable drug delivery system.Clinical Relevance— The acoustofluidic based micropump could apply for the drug administration in a safe, effective and stable form. It has potential to integrate with miniaturized sensors and electronic circuit to form portable drug delivery systems, realizing smart on-demand drug delivery.