Analysis of Volatile Organic Compounds in Exhaled Breath for Detection of Diabetes Mellitus

In recent years, lifestyle related illness has become more pronounced and demand for technology that enables easy and quick checking of diseases is increasing. Breath analysis is a very promising field of research work having great potential for diagnosis of diseases in non-invasive way for analyzing the volatile organic compounds (VOC’s) and its concentrations in exhaled human breath and also has potential for the early detection and progress monitoring of several diseases. As far as detection of Diabetes Mellitus is concerned, glucose level is calculated by invasive methods which is quite painful, time consuming and tormenting to some people, hence there has been a constant demand for the development of non-invasive, sensitive sensor system that offers fast and real-time electronic readout of blood glucose level. Responding to this we have prototyped a design of handy and non-invasive instrument which investigates the potential of breath signal analysis as a way for blood glucose monitoring with the help of an acetone gas sensor through which results can be actualized. Acetone is not only an effective biomarker of Diabetes Mellitus but also proved to be a rapid, patient compliant viable alternative to the conventional methods of blood glucose determination.