A Pulsed Electrochemistry Readout IC for Single Transistor-based Biosensor

This paper presents a portable readout interface IC for electrochemical sensing. The circuit conducts the chronoamperometry measurement by generating two stimulus pulses. A current-to-frequency converter senses the current change from the bio-sensing transistor built by two gold electrodes at the gate. The results are measured by using a time-to-digital converter. The readout circuit consumes 14$\mu$ W at a 1.2V supply, and its function is verified under the potassium ferricyanide test. The limit of detection is 1nM in a concentration range of 1mM.