Parametric ultrasound perfusion analysis combining bolus tracking and replenishment

The paper presents a new perfusion analysis method using ultrasound which combines burst-replenishment and bolustracking acquisition methods. It allows absolute quantification of the mean transit time, blood flow and blood volume. It is based on the concept of arterial input function and tissue residue function and is formulated as a blind-deconvolution problem. It is illustrated on recordings from Crohn's disease patients.