Automated diagnosis and image understanding with object extraction, object classification, and inferencing in retinal images

Medical imaging is shifting from film to electronic images. The STARE (structured analysis of the retina) system is a sophisticated image management system that will automatically diagnose images, compare images, measure key features in images, annotate image contents, and search for images similar in content. The authors concentrate on automated diagnosis. The images are annotated by segmentation of objects of interest, classification of the extracted objects, and reasoning about the image contents. The inferencing is accomplished with Bayesian networks that learn from image examples of each disease. This effort at image understanding in fundus images anticipates the future use of medical images. As these capabilities mature, the authors expect that ophthalmologists and physicians in other fields that rely in images will use a system like STARE to reduce repetitive work, to provide assistance to physicians in difficult diagnoses or with unfamiliar diseases, and to manage images in large image databases.