FCBC Hybrid Encoding Method Based on Fountain Code and Base64 Code

Fountain code is a commonly used and excellent DNA storage encoding method, but the encoding process will judge and screen the generated bases, resulting in duplicate encoding, long encoding time, and high computational resource consumption. This article proposes an FCBC hybrid coding method, which is based on fountain code coding. Base64 code is added during coding screening, and RS code is added after generating bases to control the GC content of bases at around 50% and reduce the probability of homopolymer generation. This improves the pass rate of fountain code base screening and reduces coding time. When the code length is 168, the FCBC hybrid encoding method can reduce the encoding time by 11% for a 2KB txt file compared to the encoding method without Base64 code, and by 20% for a 384KB jpg file. The FCBC hybrid encoding method can effectively reduce the encoding time using only fountain codes, and the introduction of RS codes can avoid errors such as base addition, replacement, and deletion, improving coding accuracy. In the future era of big data storage, the FCBC hybrid encoding method will help accelerate the data encoding process, reduce encoding time, save computing resources, reduce costs, and promote the development of DNA storage.