P300 Habituation within the Visual Stimulation Paradigm Based on Synchronous EEG and Eye Tracker Recordings: Pilot Study

Brain-computer interface (BCI) is a system that, based on brain signals, improves the quality of life of patients with movement disorders and can be used for medical rehabilitation. One promising neuromechanism is the P300 evoked potential, which is a cognitive evoked potential that occurs in response to a stimulus on which the user has focused his attention. However, one possible limitation of the P300 is the effect of habituation, that is, a decrease in the amplitude of the P300 during prolonged stimulation. One possible approach for quantifying the effect of habituation during visual stimulation could be eye fatigue during stimulation. Simultaneous EEG and eye tracker recording allows the relationship between these processes to be assessed. As part of the work, an experimental study involving 4 healthy subjects was performed, which included synchronous recording of EEG and eye tracker during prolonged visual stimulation. Stimulus delivery frequencies of 1 and 2 Hz were varied, as well as the position of the target letter on the monitor. As a result, P300 parameters, the number of blinks during the experimental study, as well as the integral characteristic of the amplitude of eye movements on the oculogram were evaluated. Estimated dependencies were compiled, but further expansion of the experimental sample and consideration of external factors are necessary to generalize the results obtained.