Formulating the Problem of Determination of Individual Local Minimal Erythema Dose Without Test Exposures

The article substantiates an approach to evaluate the minimal erythema dose (MED) in dermatology without test exposure. Arguments are given in support of using a number of optical noninvasive diagnostic methods for this purpose. A photosensitivity of human skin to ultraviolet radiation in the 305–315 nm waveband is determined by skin optical properties, morphological parameters of the skin and vessels' reactivity in the skin. These quantities can be measured before a treatment, so the evaluation of individual MED is not impossible.