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Therapeutic drug level testing based on Raman spectroscopy of the tear fluid
2018 11th Biomedical Engineering International Conference (BMEiCON)
Year: 2018 | Conference Paper |
Cited by: Papers (1)
We have developed the drug level testing based on Raman Spectroscopy of tear fluid. In this study, we examined the detection limit of Paper-based Surface Raman Spectroscopy (PSERS) and simulated Line and Space photonics crystal Surface Raman Spectroscopy (L/SSERS). The results implicated the usefulness of this method.Show More
Compact photoacoustic imaging system using LED light source for monitoring skin condition
2017 10th Biomedical Engineering International Conference (BMEiCON)
Year: 2017 | Conference Paper |
Cited by: Papers (1)
Non-invasively monitoring skin condition that can be performed near the patient is helpful for diagnosis of skin diseases. Photoacoustic and ultrasound imaging is one of the biomedical imaging technique. Both of these can be detected with an ultrasound transducer and can be acquired complementarily. Photoacoustic provides functional information while ultrasound provides structural information. How...Show More
Analysis of Difference in Center-of-Pressure Positions Between Experts and Novices During Asymmetric Lifting
Hieyong Jeong;Kenji Yamada;Michiko Kido;Shima Okada;Taishin Nomura;Yuko Ohno
Although numerous studies have analyzed the relationship between manual material handling (MMH) and the forces acting on the lumbar spine, the difference in the MMH between experts and novices through the analysis of measured data has not been well studied. The purpose of this paper was to analyze the difference in the MMH positions between ten skilled experts working at a freight transport compan...Show More
Analysis of Center of Pressure Location during Asymmetric Lifting
Hieyong Jeong;Kenji Yamada;Michiko Kido;Yuko Ohno;Soichiro Watanabe;Taishin Nomura
2015 IEEE International Conference on Systems, Man, and Cybernetics
Year: 2015 | Conference Paper |
Cited by: Papers (4)
We have an interest in the handling posture at the logistic workplace. Although a lot of studies on compressive and shear forces on lumbar spine have been reported, there was little studies on the difference of asymmetric lifting between logistic workers and beginners with the comparison of measured results. The main purpose of this study was to analyze the difference between ten healthy workers (...Show More
Gastric Contraction Imaging System Using a 3-D Endoscope
Kayo Yoshimoto;Kenji Yamada;Kenji Watabe;Maki Takeda;Takahiro Nishimura;Michiko Kido;Toshiaki Nagakura;Hideya Takahashi;Tsutomu Nishida;Hideki Iijima;Masahiko Tsujii;Tetsuo Takehara;Yuko Ohno
This paper presents a gastric contraction imaging system for assessment of gastric motility using a 3-D endoscope. Gastrointestinal diseases are mainly based on morphological abnormalities. However, gastrointestinal symptoms are sometimes apparent without visible abnormalities. One of the major factors for these diseases is abnormal gastrointestinal motility. For assessment of gastric motility, a ...Show More
Evaluating the effectiveness of vascular access imaging device in training of new graduate nurses
2014 IEEE Healthcare Innovation Conference (HIC)
Year: 2014 | Conference Paper |
Peripheral intravenous (IV) line placement is one of the most invasive and painful procedures performed by nurse. Although it is a common nursing procedure, sufficient and effective skill training is necessary before encountering patients, especially for new nurses. Vascular access devices (VADs) are now developed and introduced in hospitals, however, the effectiveness for the training among the n...Show More
A study on estimating blood pressure during body postural change based on pulse transit time
Hieyong Jeong;Mari Hayashi;Masaki Sekine;Toshiyo Tamura;Michiko Kido;Kenji Yamada;Yuko Ohno
2014 IEEE Healthcare Innovation Conference (HIC)
Year: 2014 | Conference Paper |
Cited by: Papers (6)
We are interested in healthcare for a bed ridden patient. Although a bed ridden patient in the hospital can be led to a circulatory disorder or a serious secondary disease, it is still difficult to give an adequate healthcare service for the patient due to side effects. Thus, we focus on the method of measuring the continuous and non-invasive bio signal in order to provide important insight into t...Show More
Paper-based Raman spectroscopy for on-site therapeutic drug monitoring
2014 IEEE Healthcare Innovation Conference (HIC)
Year: 2014 | Conference Paper |
This study proposes Raman spectroscopy of tear fluid with paper substrates for on-site therapeutic drug monitoring(TDM). In this method, the paper substrates are used for tear sample collection and measurement. The use of paper offers a minimally-invasive, simple, and inexpensive method for therapeutic drug monitoring. To demonstrate the usability of the paper substrates for this purpose, we measu...Show More
Forward kinematic solution through geometry analysis for rehabilitation cable robot
Hieyong Jeong;Soichiro Watanabe;Kenji Yamada;Kiyoshi Yoshida;Michiko Kido;Yuko Ohno
The 7th 2014 Biomedical Engineering International Conference
Year: 2014 | Conference Paper |
We have an interest in the forward kinematic solution of a three-DOF cable-driven parallel end effecter for rehabilitation of the upper limbs. Although to solve the forward kinematic solution is to decide the position and orientation of end effecter by using four given cable lengths, it is well known that it is difficult to make sure the only solution among multiple solutions of cable-driven paral...Show More
Effectiveness evaluation of waist support tool through human posture balance
Saki Shimizu;Hieyong Jeong;Michiko Kido;Eiji Miyoshi;Kenji Yamada;Yuko Ohno;Taishin Nomura;Soichiro Watanabe;Kazuo Torigai;Masanobu Hayashi
The 7th 2014 Biomedical Engineering International Conference
Year: 2014 | Conference Paper |
Cited by: Papers (2)
A lot of carrying workers wonder whether it is good to wear a waist support tool to protect the waist or not. Although the qualitative analysis of waist support tool is generally used for the evaluation, there is not yet the evaluation of quantitative analysis. In this paper, we proposed the method of quantitative analysis in order to evaluate the effectiveness of waist support tool through human ...Show More
Optimization of workspace through perturbation analysis of rehabilitation cable robot
Hieyong Jeong;Soichiro Watanabe;Kenji Yamada;Kiyoshi Yoshida;Michiko Kido;Yuko Ohno
The 7th 2014 Biomedical Engineering International Conference
Year: 2014 | Conference Paper |
Cited by: Papers (2)
It is well known that planar robots may have singular configurations that can result in a loss of full control the mechanisms. In fact, the uncontrollable area is existed as close to singularity, although the robot is operated inside the analyzed workspace. According to the distance to singularity, this comes from the difference of the sensitivity of singular values to be changed easily through th...Show More
A difference of human posture between beginner and expert during lifting a heavy load
Soichiro Watanabe;Kazuo Torigai;Masanobu Hayashi;Hieyong Jeong;Saki Shimizu;Michiko Kido;Taishin Nomura;Eiji Miyoshi;Kenji Yamada;Yuko Ohno
The 7th 2014 Biomedical Engineering International Conference
Year: 2014 | Conference Paper |
Cited by: Papers (3)
We focused on what is the difference of human posture during lifting a heavy load between a beginner and an expert who has been working in the logistics industry. Although there have been a lot of studies to analyze the human motion through the mathematical modeling, we proposed the method to estimate the bending angle of human upper body through the analysis of the human balance by using the Nint...Show More
Enhancing effect of tangential vibration on human vibrotactile sensitivity
2014 World Automation Congress (WAC)
Year: 2014 | Conference Paper |
Vibrotactile sensitivity is usually defined by the minimum amplitude when subjects perceive the vibration with a frequency which generates to the perpendicular direction on the skin surface. In this paper, we are interested in how the vibrotactile sensitivity with a frequency is changed under the condition adding the tangential vibration with the other frequency which generates to the tangential d...Show More
Fluorescence amplification based on DNA structural changes for enzyme-free detection of microRNA
Takahiro Nishimura;Kenji Yamada;Yuko Ohno;Yusuke Ogura;Jun Tanida
2014 World Automation Congress (WAC)
Year: 2014 | Conference Paper |
For sensing biomarkers on site, this paper discusses detection of a microRNA (miRNA) by positional control of fluorescence molecules with DNA reactions. We designed a hybridization chain reaction-based system that can detect and amplify molecular signals as fluorescent signals without temperature control and enzymatic reactions. A target miRNA triggers to make a polymer structure by opening hairpi...Show More
Feasibility study of paper-based surface enhanced Raman spectroscopy of tear fluids for onsite therapeutic drug monitoring
Moe Yokoyama;Takahiro Nishimura;Kenji Yamada;Michiko Kido;Yuko Ohno;Yoshiaki Sakurai;Daiki Mita;Yoshinori Yamaguchi;Eiichi Tamiya;Toshiaki Nagakura
This paper discuss drug concentration measurement based on Raman spectroscopy of tear fluids with paper substrates for on-site therapeutic drug monitoring (TDM). We focus on tear fluids as alternative specimens to blood for minimally-invasive TDM. By using paper substrates, specimen collection and measurement based on surface enhanced Raman spectroscopy will be performed easily and inexpensively. ...Show More
Feasibility study of paper-based surface enhanced Raman spectroscopy of tear fluids for onsite therapeutic drug monitoring
Moe Yokoyama;Takahiro Nishimura;Kenji Yamada;Michiko Kido;Yuko Ohno;Yoshiaki Sakurai;Daiki Mita;Yoshinori Yamaguchi;Eiichi Tamiya;Toshiaki Nagakura
Year: 2014 | Conference Paper |
Amplification and encoding of biomolecular signals with designed reactions of DNA
Takahiro Nishimura;Kenji Yamada;Yuko Ohno;Yusuke Ogura;Jun Tanida
The 6th 2013 Biomedical Engineering International Conference
Year: 2013 | Conference Paper |
Cited by: Papers (2)
This paper focuses on a biomolecular detection method based on amplification and encoding with DNA reactions. For proof of the concept, we demonstrate that encoding of molecular signal with amplification is achievable using a hybridization chain reaction with fluorescence resonance energy transfer.Show More
Proposal of estimation method for drug concentration in blood by Raman spectroscopy of tear fluids
Moe Yokoyama;Takahiro Nishimura;Kenji Yamada;Yuko Ohno;Yoshiaki Sakurai
The 6th 2013 Biomedical Engineering International Conference
Year: 2013 | Conference Paper |
Cited by: Papers (1)
Drug concentrations in blood are good indexes for drug therapy. This study proposed an approach based on Raman spectroscopy of tears for a rapid and minimally invasive monitoring of the concentration. Tear fluid reflects the drug concentration in blood and its collection can be performed easily and noninvasively in comparison to blood drawing. Raman spectroscopy is a rapid and sensitive analytical...Show More
Dual-band multi-aperture enhanced redox imaging of colonic adenomas for endoscopes with a high-performance CMOS imager
K. Kagawa;B. Zhang;M.-W. Seo;S. Kawahito;Y. Kominami;K. Yamada;S. Yoshida;S. Tanaka
2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Year: 2013 | Conference Paper |
Cited by: Papers (2)
Dual-band multi-aperture imaging of colonic adenomas based on the redox condition of mucosal cells for next-generation endoscopes is proposed. A low-noise and high-dynamic-range CMOS imager with the folding integration and the cyclic ADC is utilized in the single-imager multi-aperture camera system with 475-nm and 530-nm band-pass filters. A redox image is calculated from four kinds of images, 475...Show More
Biosignal-based relaxation evaluation of head-care robot
Takeshi Ando;Maki Takeda;Tomomi Maruyama;Yuto Susuki;Toshinori Hirose;Soichiro Fujioka;Osamu Mizuno;Kenji Yamada;Yuko Ohno;Honda Yukio
2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
Year: 2013 | Conference Paper |
Cited by: Papers (4)
Such popular head care procedures as shampooing and scalp massages provide physical and mental relaxation. However, they place a big burden such as chapped hands on beauticians and other practitioners. Based on our robot hand technology, we have been developing a head care robot. In this paper, we quantitatively evaluated its relaxation effect using the following biosignals: accelerated plethymogr...Show More
Variable field-of-view visible and near-infrared polarization compound-eye endoscope
K. Kagawa;R. Shogenji;E. Tanaka;K. Yamada;S. Kawahito;J. Tanida
2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Year: 2012 | Conference Paper |
Cited by: Papers (5)
A multi-functional compound-eye endoscope enabling variable field-of-view and polarization imaging as well as extremely deep focus is presented, which is based on a compact compound-eye camera called TOMBO (thin observation module by bound optics). Fixed and movable mirrors are introduced to control the field of view. Metal-wire-grid polarizer thin film applicable to both of visible and near-infra...Show More
Endoscopic compound-eye camera with extended depth of focus
2011 ICO International Conference on Information Photonics
Year: 2011 | Conference Paper |
Cited by: Papers (2)
A focusing-free and multispectral three-dimensional endoscope based on a compact compound-eye camera called TOMBO (thin observation module by bound optics) is proposed. A prototype endoscopic TOMBO with 3×2 aspherical lenses using a wavefront coding technique and a 640×480-pixel color image sensor demonstrates extended depth of focus and depth estimation.Show More
Study on measurement of water content in human body by impedance method
Kouhei Hisamori;Takeshi Abe;Yoshikazu Maekawa;Yoko Akiyama;Fumihito Mishima;Kenji Yamada;Shigehiro Nishijima
2010 World Automation Congress
Year: 2010 | Conference Paper |
In an aged society, the problem of urine incontinence is becoming more serious. Urine incontinence is a considerable factor in lowering the QOL (quality of life) of both elderly people and care workers. It is important to understand the micturition desire of elderly people in advance and to take appropriate care. Bioelectrical impedance analysis is one of the low cost and portable methods of exami...Show More
Development of new type tactile endoscope with silicone rubber membrane
Yuto Susuki;Kenji Yamada;Sachiko Shimizu;Yuko Ohno;Toshiaki Nagakura;Ken Ishihara
2010 World Automation Congress
Year: 2010 | Conference Paper |
We have developed new type tactile endoscope with silicone rubber membrane. The system consists of silicone rubber membrane, image sensor and illumination system. A surface of the Silicone rubber membrane has any patterns which made by nanotechnology. This pattern is deformed by pressing tissue such as cancer, colon and so on. The deformed pattern is captured by image sensor. This pattern is analy...Show More
Development of new type incontinence sensor using RFID tag
Kenji Yamada;Nagakura Toshiaki;Ken Ishihara;Yuko Ohno;Atsue Ishii;Sachiko Shimizu;Tomoyuki Araki;Rie Takahashi;Hideya Takahashi;Eiji Shimizu
2010 IEEE International Conference on Systems, Man and Cybernetics
Year: 2010 | Conference Paper |
Cited by: Papers (5)
Disposable diaper is heavy used in care home or hospital. It's often the case that helper doesn't notice that the patient eliminated. This is very discomfort for patient, and bad for the health. They are problem which should be solved. There are conventional incontinence sensor using gas sensor or capped electrode etc. Most of them are large size. So the patient feels something is wrong when he ge...Show More
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