Titanium Dioxide-Graphene-Black Phosphorus-Based SPR Sensor for Helicobacter Pylori Bacteria Detection

Helicobacter pylori (
H. pylori
) plays a significant role in the development of various gastrointestinal diseases. It is a form of bacteria that infects the first part of the small intestine (duodenum). This bacterium is a common cause of peptic ulcers. This paper presents two surface plasmon resonance (SPR) sensors for the detection of
H. pylori
. Sensors 1 and 2 consist of a structure of prism-Ag-Tio
₂
-graphene-BP-SM and prism-Au-Tio
₂
-graphene-BP-SM, respectively. This work takes advantage of the excitement of surface plasmons and evanescent waves at the metal-dielectric interface. The angular interrogation technique is used to analyze the proposed sensors at a wavelength of 633 nm. Results show that sensor 1 furnishes the maximum sensitivity of 321.43°/
RIU
Quality factor (QF) of 57.09
RIU
^-1
, dip of figure of merit (DFoM) of 5974.53 and Combined sensitive factor (CSF) of 52.63, and sensor 2 endows the maximum sensitivity of 261.25°/
RIU
, QF of 30.41
RIU
^-1
, DFoM of 22, 139 and CSF of 28.21. The results furnish a substantial improvement in comparison to the reported work in the literature. Finally, the field distributions of the proposed sensor are exhibited using the COMSOL software.