Neuroimaging Precision: Crafting a Stacked VGG19-Logistic Fusion for Breakthrough Early Detection of Alzheimer's

Several medical investigations have demonstrated that Alzheimer's disease (AD) manifests itself long before the formal diagnosis of dementia. These studies have led to the identification of numerous ideal biomarkers associated with Alzheimer's symptoms. Consequently, the imperative for early diagnosis has become evident, necessitating a high-performance computational tool capable of efficiently processing vast amounts of data. Early detection of AD not only offers valuable insights into the condition's progression but also presents a significant opportunity to benefit from timely and effective treatment. This ground-breaking study pioneers an innovative approach to the early detection and diagnosis of AD by crafting a sophisticated model SVGGL, which blends the power of stacked VGG19 neural networks with the interpretability of logistic regression. Leveraging neuro-imaging data, specifically the insights provided MRI, and our model aims to discern subtle structural and functional alterations in the brains of individuals at risk for or in the early stages of AD. The combination of feature extraction from stacked VGG19 models and subsequent logistic regression classification yields a precise and efficient classifier with an outstanding accuracy of 98.24%. With such a high degree of accuracy, the model can reliably differentiate among healthy people and those with Alzheimer's, opening the door to potential early intervention and individualized treatment plans. The study not only sheds light on the intricate neuro pathological landscape of AD but also propels us toward a future where cutting-edge technology and data-driven insights, exemplified by our high-accuracy model, converge to tackle the challenges posed by this prevalent neurodegenerative disorder.