Metallonanoparticles with antibacterial and anticarcinogenic activity extracted from Cinnamomum zeylanicum bark

Nanoparticles are one of a kind for their size, shape and diverse applications. A blend of metallic nanoparticles with herbs improves its properties and application than bulk materials. Synthesis of zinc oxide from Cinnamomum zeylanicum bark is done by sol-gel treatment. UV-visible spectroscopy results clearly indicate the absorption peak of ZnO nanoparticles. Fourier transform infrared spectroscopy confirmed the presence of phytochemicals and zinc oxide vibration in crystalline structure. X-ray diffraction exhibited a hexagonal wurtzite structure and confirmed the presence of crystalline structure while scanning electron microscopy report revealed the average particle size of about 70 nm and of spherical shape. Moreover, the antibacterial activity of Cinnamon derived nanoparticles against two main bacterial strains such as Staphylococcus aureus, Bacillus subtilis were assessed by agar well diffusion method. By cytotoxicity assay, lethal effect was determined. Also, we determined the anticancer activity of Cinnamon in HepG2 cell line. Thus the study reveals the synthesized Cinnamon derived zinc oxide nanoparticles serve as an excellent alternative source of antibacterial agent and an anticancer property, can be used for cancer treatment.