Long-term PM2.5 Exposure, Genome-wide DNA Methylation and Lung Function in Korean Adults

This study aimed to investigate how the change of DNA methylation mediates the association between long-term exposure of PM
2.5
and lung function (FVC, FEV
1
and FEV
1
/FVC). Three CpGsites(cgl2233418 in CTDPI, cg00020794 in FAM38A and cg24202654 in GADI) were mediators of the association between PM
2.5
and lung function.