New Nanocatalitic Fe3O4/CeO2 Composite in the Cyclocondensation Reaction

A catalytic method for the synthesis of 2-aminopyrimidine derivatives based on the condensation reaction of 1,3-dicarbonyl compounds with guanidine derivatives is proposed. The efficiency of using magnetic nanosized catalytic $\mathrm{Fe}_{3}\mathrm{O}_{4}/\mathrm{CeO}_{2}$ composite is demonstrated, an increase in the yield of the targeted organic product by 20%, the synthesis time reduced from 6 h to 3 h.