Effect of PID Controller on Blood Glucose Concentration for Varying Plasma Insulin, Independent Glucose Flux, Renal Glucose Clearance and Gut Absorption Rate

This paper represents the effect of the FID (proportional-integral-derivative) controller over glucose concentration for the variables plasma insulin, gut absorption rate, renal clearance, and independent glucose flux in the human body. The undesirable glucose concentration is drawn to the desired level by using a PID controller. The proper concentration of glucose plays a vital role in occurring the typical operation of organs in the human body. Three subsystems are included in the proposed model such as insulin subsystem, glucose subsystem and the influence of glucose subsystem. The models for all the subsystems are achieved by using the model constants given by the HOVORKA model. The effect of variation of the variables on glucose concentration with the PID controller is observed by MATLAB Simulink. The changes illustrate that the level of glucose concentration for the human body implementing the PID controller is accurate than the open-loop glucose concentration.