I. Introduction
Central dogma is an inevitable process for any living entity which is having two phases, transcription where DNA is transcribed into mRNA and translation where every three consecutive nucleotides, called as codon, is translated into amino acid chains which result in protein [1]. The stop codons split the protein into pieces which have their own functionalities. Proteins are essential part of cells that regulates biological processes and functionalities. Among the twenty amino acids, some are very susceptible to random modifications. The modification occurs after the formation of proteins, that's why it is called post-translational modifications. Butyrylation [2], sumoylation [3], glutarylation are some examples. These modifications can occur in one or more amino acids, known as responsible residues. Sometimes these modifications bring diversity to species by changing the functions of living cells, occasionally it results in severe diseases as a consequence [4].