Genome-wide association study identified genetic variants associated with severity of COPD in Korean participants

Chronic Obstructive Pulmonary Diseases (COPD) is a complex disease with considerable variability affecting about 65 million individuals [1]. We therefore performed a genome-wide association study (GWAS) of COPD severity. Thirty-four genetic variants were identified (P <; 1.0×10
^-5
), and were located in intron and upstream/downstream regions. In conclusion, these genetic markers could provide insight into the understanding the pathological process of COPD.