Multi-factor modeling of OCT-scan formation in the presence of scatterer motions

We present a robust semi-analytical multi-factor model of OCT-scan formation with rigorous accounting for the beam-focusing effects. It is based on numerical summation of the contributions of the localized sub-resolution scatterers, accounting for variations in the phase-amplitude parameters of the incident and backscattered optical waves, with a subsequent integration of the latter over the objective aperture. The main advantage of presented model is its convenience to account for scatterer motions in comparison with classical Monte-Carlo OCT-simulation approaches. In view of difficulties in performing highly-controlled phantom experiments, application of an adequate numerical model opens very flexible and convenient possibilities for evaluating the influence of scatter motions using numerically simulated OCT scans. The numerical model readily allows one to introduce various (e.g., regular/irregular or mixed) types of scatterer motions.