Simulation of the south-eastern Polish subpopulations behaviour

Using the large database of STR (Short Tandem Repeat) DNA results of south-eastern Polish population were validated with regard to the correctness of data by testing the interdependence of loci and the Hardy-Weinberg hypothesis. It turned that the data was correct so that this topic was given up. Furthermore, dividing this population according to the place of birth, we evaluated the F
_ST
, Nei's distance value and other measures used in Phylogenetics, of the subpopulations chosen in that way. phylogenetic trees for this supopulation were obtained and the focus was made validation of hierarchical classifications. We evaluate classifications with the Dunn's index, and compared the inter classifications using the cophenetic correlation of classifications. After comparing and validating the classification methods the behaviour of these distances was simulated in the following generations. We gathered information about migration (emigration as well as immigration) rate in the considered subpopulation. Therefore changes of phenotype frequencies could be simulated in the these generations based on some reasonable assumptions. On the basis of these simulated frequencies the future distance arrays were computed. If the maximum of this distance is smaller than the assumed level, we state that differences between the subpopulations vanish. We focus on the number of generations till all the differences vanish. It is worthwhile mentionary that the migrations in south-eastern Poland are significant, thus that number is relatively small.