Modelling the Concentration Changes of 18F-FDOPA using Compartmental Model in Parkinson Patients

The study on the concentration changes of the radioactive substance
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F-FDOPA in striatum is one of the important technique to diagnose the Parkinson's disease (PD). In research, the compartment model is applied to study the area proportions of
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F-FDOPA through the brain in the striatum area and consider different concentration levels at a given time t. In particular, we adopt compartmental dynamic model to study the behaviour of
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F-FDOPA over times after the injection. We also compute the modelling errors and give subsequent discussion about our results.