Network Formation Model of Bio-nanomachines Based on Directed Migration and Adhesion

A bio-nanomachine network is useful in diverse applications of molecular communication. In this paper, we develop a network formation model of bio-nanomachines based on how vascular endothelial cells form a blood vessel-like structure. In our model, bio-nanomachines migrate toward each other using attractant molecules. When two bio-nanomachines move close to each other, they adhere to form a physical connection or a link between them. In this way, a group of bio-nanomachines forms a network collectively. We perform computer simulations using the model to identify critical parameter values at which a large-scale bio-nanomachine network emerges. The model developed in this paper helps us design synthetic communication networks of bio-nanomachines.