Development of Deployable Catheter for Minimally Invasive Surgery Guidewire Application

Renal denervation procedure has been developed as a potential treatment for resistance hypertension or treatment-resistant hypertension. Renal denervation catheter was employed as a surgical tool to ablate the renal nerve with radio frequency (RF) pulses or ultrasound energy. Ensuring the proper contact of the electrical heater on the artery wall is critical, as excessive force or pressure could damage the artery wall. Non-contact ablation would not be able to perform the denervation operation effectively. The electrode size, overall packaging size and stiffness need to be calculated and analyzed to achieve the design for manufacturability (DFM). Ansys static structural system was used to optimize the design, the results shows that for the mini electrode with overall size of 0.6mm × 1.8 mm × 0.2 mm, 1.0mm deformation with 0.226MPa stress has a safety factor of 5 is recommended. The detailed chip level simulation shows that the force sensor chip with 150um bump has better sensitivity.