Computer Modelling of Cardiac Cells Electrical Activity

The electrical restitution property of cardiomyocytes is studied in the paper. The parallel conductance model, improved for the heart cells, is used to simulate the action potential (AP) and ions currents for K
⁺
, Na
⁺
, Ca
²⁺
channels. The steep areas of electrical restitution curves for ventricular cardiomyocytes are obtained. The electrophysiological phenomenon of the sudden changes in heart rate at proposed stimulation protocol is demonstrated.