Porphyrinic photodiagnosis agents: Comparative studies in aqueous, buffer and albumin-containing solutions

The optical and fluorescent properties of the modern preparations (Fotoditazin, Radachlorin, Photolon, Dimegin) have been studied and compared. These agents are used for Photodiagnosis and Photodinamic therapy of tumors. The spectroscopic studies were carried out on the preparations dissolved in different water-based media and their values of fluorescence quantum yields have been calculated too. The various media were prepared in order to model the porhyrins' behavior in the blood with different degrees of approximation.