In-situ re-calibration of implanted pressure sensors

Feasibility of the novel utilization of a pressure switch mechanism for re-calibrating drifted implanted pressure sensors in-situ is demonstrated. We have designed and characterized the pressure response of a system, which can quantify the offset of a sensor after it has been implanted. The benchtop device is constructed of a 25 pm thick titanium diaphragm with 10 mm working diameter. An optimization algorithm detected a characteristic change in the pressure response produced by the activation of a pressure switch. The repeatability of detection across three sensors is within ±0.23 mmHg over 8 pressurization cycles.