Plasmonic Nanobiosensor for Detection of in Aqueous Samples

Escherichia coli
is a prevalent pathogen for several fatal ailments, including dysentery, typhoid fever, viral and bacterial gastroenteritis, hepatitis A, diarrhea, and others. Diagnosing a pathogen is indeed a global subject targeting safe public health. Various conventional detection techniques, including bacterial culture, polymerase chain reaction, or enzyme-linked immunosorbent assay, are highly time-consuming and necessitate skilled manpower. This letter demonstrates the development of an efficient plasmonic sensing technique for sensitively detecting
Escherichia coli
in water. Herein, plasmonic nanostructures—gold nanorods have been immobilized with complementary aptamers for detecting the targeted pathogen up to a limit of detection of 0.91 CFU/mL. The developed platform could be applicable in developing a point-of-detection device for various other pathogen detection.