Research on Optical Flow Model Based Large Deformation Ultrasound-MRI Registration

A new registration method between ultrasound (US) image and Magnetic resonance imaging (MRI) was presented, and a robust optical flow model for large deformation between US image (floating image) and MRI (reference image) was built, then the vector flow field was estimated. The proposed algorithm contends with larger deformation and performs well not only for local deformation but also for global deformation. Qualitative and quantitative analyses of multiple group comparison experiments showed that registration results using the proposed method led to the best registration results.