Local Accumulation of Ferromagnetic Particles by Controlling Frequency of Rotating Magnetic Field

A novel cancer treatment with low side effect and less invasiveness by blocking newborn blood vessels around the diseased part was proposed. Ferromagnetic particles administered into the body are accumulated in the newborn blood vessels using a rotating magnetic field (RMF), and then are aggregated to block the blood vessels. We proposed a system consisting of four superconducting magnets and a cylindrical magnetic shielding material with a slit to apply the RMF to the human body. The purpose of this study was to accumulate particles locally within a spherical range of 10 mm in diameter. The results of fundamental experiments with neodymium magnets and particle trajectory calculations showed that the range of particle accumulation could be controlled by adjusting the frequency of the RMF.