Virus detection by monitoring its radio frequency response versus temperature

The use of radio frequency techniques is increasing in various applications in biodetection as well diagnostic and therapeutic medicine. This work reports for radio frequency labelfree based systematic biodetection platform; which can be used to identify several types of viruses. The presented technique is able to identify the virus type with few minutes without the use of any biomarkers. A coaxial waveguide structure is used to host the specimen enabling its measurements. Four different types of virus-mixture samples have been prepared and are involved in this study: HIV, FIV, MMTV and MPMV. Then microwave measurements have been conducted using these mixtures at different temperatures, 7°C, 37°C and 47°C, respectively. The frequency-temperature behaviour reveals the possibility to identify the kind of the virus. The change in S
₁₁
parameter level is due to the associated intrinsic °C differential resistance of the virus itself. Hence the virus is modeled as a smart material that exhibits certain loss or gain dispersion over frequency.