A Flower-Like MoS2 Nanosheet-Au Nanoparticle Composite for Sensitive Electrochemical Detection of Levodopa in the Presence of Uric Acid

Three dimensional nano-structures often exhibit excellent functional properties. In this work, MoS
₂
nanosheet flowers were hydrothermally prepared, and carboxylated gold nanoparticles were then self-assembled on the MoS
₂
nanosheet flowers. The results show that MoS
₂
NSFs with a diameter of 200 nm were composed of MoS
₂
nanosheets, and Au NPs are distributed on its surface. A MoS
₂
NSF-Au NP suspension was sprayed onto an indium tin oxide coated glass surface as an electrode for the detection of levodopa in the presence of uric acid. The results show that the electrode has ultra-high sensitivity of
$2.64~\mu \text{A}$
.
$\mu \text{M}^{-1}$
.cm
⁻²
, low limit of detection (LOD) (
$0.04~\mu \text{M}$
, S/N = 3), good anti-interference, repeatability, reproducibility and stability. Moreover, it shows satisfactory results in real-life urine samples, illustrating the potential application to the field of clinical medicine.