The Improvement of Chemovirotherapy Effectiveness Utilizing Hybrid GA-PSO

This paper investigates the potential of chemovirotherapy as a cancer treatment that combines chemotherapy and virotherapy. The article examines how various factors and initial conditions can affect the treatment’s success. The study aims to evaluate the effectiveness of chemovirotherapy using constant and non-constant infusion treatments while minimizing cancer cells and optimizing drug dosage to reduce side effects. Evolutionary algorithms were utilized to create an ideal treatment schedule to achieve optimal protocol. The results show that only the combined treatment method was successful in permanently suppressing cancer, and by optimizing the treatment, lower doses of chemotherapy drugs could be used with better outcomes.